SCHEMBL3120573

SCHEMBL3120573

CC(=O)Cc1cc2ccccc2[nH]1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.60
MTNR1B P49286 1/20 0.60
LOXL2 Q9Y4K0 1/20 0.55
NLRP3 Q96P20 1/20 0.54
FLT3 P36888 1/20 0.50
IDO1 P14902 1/20 0.49
KDM4E B2RXH2 3/20 0.49
MAPT P10636 2/20 0.49
DAO P14920 2/20 0.49
HPGD P15428 1/20 0.49
SRD5A2 P31213 1/20 0.49
HSD17B10 Q99714 1/20 0.49
GSK3B P49841 1/20 0.48
ALDH1A1 P00352 2/20 0.47
GAA P10253 1/20 0.47
MAPK1 P28482 1/20 0.47
HRH4 Q9H3N8 1/20 0.46
HDAC3 O15379 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC2 Q92769 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9027547 0.85 LOXL2 (0.58) MTNR1AMTNR1BLOXL2NLRP3KDM4E
SCHEMBL3451201 0.85 LOXL2 (0.58) MTNR1AMTNR1BLOXL2NLRP3FLT3
SCHEMBL31336079 0.84 LOXL2 (0.56) MTNR1AMTNR1BLOXL2NLRP3FLT3
SCHEMBL49270 0.84 LOXL2 (0.56) MTNR1AMTNR1BLOXL2NLRP3FLT3
SCHEMBL29365671 0.84 LOXL2 (0.56) MTNR1AMTNR1BLOXL2NLRP3FLT3
SCHEMBL12714834 0.83 MTNR1A (0.66) MTNR1AMTNR1BLOXL2NLRP3FLT3
SCHEMBL27736989 0.83 MTNR1A (0.54) MTNR1AMTNR1BLOXL2NLRP3FLT3
SCHEMBL31514826 0.82 LOXL2 (0.55) MTNR1AMTNR1BLOXL2NLRP3IDO1
SCHEMBL31511816 0.82 LOXL2 (0.55) MTNR1AMTNR1BLOXL2NLRP3FLT3
SCHEMBL630523 0.82 SIRT1 (0.64) MTNR1AMTNR1BLOXL2NLRP3FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119306681-A Synthesis method of 3-oxazoline-5-ketone and derivative thereof 湖南医药学院 2025-01-14 CN claimed
CN-113862234-B Transaminase and application thereof in preparation of (R) -alpha-methyl tryptamine compound 弈柯莱生物科技(集团)股份有限公司 2024-09-10 CN claimed
CN-113862234-A Transaminase and application thereof in preparation of (R) -alpha-methyltryptamine compounds 弈柯莱生物科技(上海)股份有限公司 2021-12-31 CN claimed
US-10143679-B2 Phytoestrogen compositions and associated methods NSE PRODUCTS, INC. (US) 2018-12-04 US claimed
US-20180271834-A1 PHYTOESTROGEN COMPOSITIONS AND ASSOCIATED METHODS NSE PRODUCTS, INC. (US) 2018-09-27 US claimed
CN-106795531-A Methods, reagents and cells for biosynthesis of compounds 英威达技术有限责任公司 2017-05-31 CN claimed
CN-105189764-A Methods of producing 7-carbon chemicals via C1 carbon chain elongation associated with coenzyme B synthesis INVISTA TECH SARL 2015-12-23 CN claimed
CN-104903455-A Method for biosynthesis of isobutene INVISTA TECH SARL 2015-09-09 CN claimed
CN-104768560-A Diagnosis and treatment of autism spectrum disorders CALIFORNIA INST OF TECHN 2015-07-08 CN claimed
US-20150005360-A1 PHYTOESTROGEN COMPOSITIONS AND ASSOCIATED METHODS NSE PRODUCTS, INC. (US) 2015-01-01 US claimed
CN-102317464-B Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks CELEXION, LLC (US) 2014-10-29 CN claimed
CN-102317464-A From alpha-ketoacid biosynthesizing difunctionality alkane CELEXION LLC 2012-01-11 CN claimed
CN-100390189-C Production of 2 '-deoxynucleosides and 2' -deoxynucleoside precursors from 2-dehydro-3-deoxy-D-gluconic acid EVOLOGIC S A (FR) 2008-05-28 CN claimed
CN-1832954-A Production of 2 '-deoxynucleosides and 2' -deoxynucleoside precursors from 2-dehydro-3-deoxy-D-gluconic acid EVOLOGIC S A (FR) 2006-09-13 CN claimed
CN-1207569-C Method for assaying virus-containing sample, virus assaying method and diagnostic kit ADVANCED LIFE SCIENCE INST INC (JP) 2005-06-22 CN claimed
CN-1330716-A Method for controlling gene expression in bacteria, i.e., Agrobacterium rhizogenes, to improve root nodule development, nitrogen fixation, and plant biomass production G IN E ST R A SOCIETA CONSORTI (IT) 2002-01-09 CN claimed
CN-1239548-A Method for detecting or determining viruses TONEN CORP (JP) 1999-12-22 CN claimed
EP-0025727-B1 INDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM SANOFI S.A. (FR) 1984-03-28 EP claimed
EP-0025727-A1 Indole derivatives, process for their preparation and medicaments containing them SANOFI S.A. (FR) 1981-03-25 EP claimed
CN-118956653-B Probiotic with uric acid reducing activity, composite probiotic agent and application thereof 齐鲁工业大学(山东省科学院) 2025-03-18 CN disclosed
CN-119615198-A Electrocatalytic oxidation modification method for indole skeleton-containing compound 浙江工业大学 2025-03-14 CN disclosed
CN-119306681-A Synthesis method of 3-oxazoline-5-ketone and derivative thereof 湖南医药学院 2025-01-14 CN disclosed
CN-118956653-A Probiotic with uric acid reducing activity, composite probiotic agent and application thereof 齐鲁工业大学(山东省科学院) 2024-11-15 CN disclosed
CN-113862234-B Transaminase and application thereof in preparation of (R) -alpha-methyl tryptamine compound 弈柯莱生物科技(集团)股份有限公司 2024-09-10 CN disclosed
CN-113862234-B Transaminase and application thereof in preparation of (R) -alpha-methyl tryptamine compound 弈柯莱生物科技(集团)股份有限公司 2024-09-10 CN disclosed
CN-117925502-B Shinyleaf yellowhorn tissue culture solution 山东沃奇农业开发有限公司 2024-07-05 CN disclosed
CN-117925502-A Shinyleaf yellowhorn tissue culture solution 山东沃奇农业开发有限公司 2024-04-26 CN disclosed
CN-107312028-B Halogenated organoaminosilane precursors and methods of depositing thin films comprising the same 弗萨姆材料美国有限责任公司 2023-04-14 CN disclosed
CN-115896823-A D 2 Method for preparing alpha, beta-deuterated amine medicine and prodrug by electrocatalysis of nitrile with O as deuterium source 天津大学 2023-04-04 CN disclosed
CN-112891343-B Application of 3-indole acetonitrile in preparing medicine for inhibiting novel coronavirus SARS-CoV-2 华中农业大学 2022-04-01 CN disclosed
CN-113862234-A Transaminase and application thereof in preparation of (R) -alpha-methyltryptamine compounds 弈柯莱生物科技(上海)股份有限公司 2021-12-31 CN disclosed
CN-113862234-A Transaminase and application thereof in preparation of (R) -alpha-methyltryptamine compounds 弈柯莱生物科技(上海)股份有限公司 2021-12-31 CN disclosed
CN-112891343-A Application of 3-indole acetonitrile in preparing medicine for inhibiting novel coronavirus SARS-CoV-2 华中农业大学 2021-06-04 CN disclosed
CN-105209626-B 3- hydracrylic acid is produced by recombination yeast 诺维信股份有限公司 2019-09-03 CN disclosed
US-10143679-B2 Phytoestrogen compositions and associated methods NSE PRODUCTS, INC. (US) 2018-12-04 US disclosed
US-20180271834-A1 PHYTOESTROGEN COMPOSITIONS AND ASSOCIATED METHODS NSE PRODUCTS, INC. (US) 2018-09-27 US disclosed
CN-107828671-A For producing the composition and method of 3 hydracrylic acids 卡吉尔公司 2018-03-23 CN disclosed
CN-107746834-A For preparing the method and intermediate of Pregabalin 辉瑞爱尔兰制药公司 2018-03-02 CN disclosed
CN-107709568-A Method for producing and processing diamines 基因组股份公司 2018-02-16 CN disclosed
CN-107586753-A Collaboration produces isopropanol and primary alconol, the microorganism and method of dihydric alcohol and acid 基因组股份公司 2018-01-16 CN disclosed
CN-107556273-A For preparing the method and intermediate of Pregabalin 辉瑞爱尔兰制药公司 2018-01-09 CN disclosed
CN-107406821-A For producing the mutation host cell of 3 hydracrylic acids 诺维信公司 2017-11-28 CN disclosed
CN-105051022-B Process and intermediates for the preparation of pregabalin 辉瑞爱尔兰制药公司 2017-10-27 CN disclosed
CN-107109444-A Method and material for producing 6-carbon monomers 英威达技术有限责任公司 2017-08-29 CN disclosed
CN-107109347-A Recombinant host cell for producing 3 hydracrylic acids 诺维信公司 2017-08-29 CN disclosed
CN-106795534-A Method, reagent and cell for biosynthesis compound 英威达技术有限责任公司 2017-05-31 CN disclosed
CN-106795531-A Methods, reagents and cells for biosynthesis of compounds 英威达技术有限责任公司 2017-05-31 CN disclosed
CN-106795530-A Methods, reagents and cells for biosynthesis of compounds 英威达技术有限责任公司 2017-05-31 CN disclosed
CN-104388443-B Strawberry auxin synthetic rate-limiting enzyme gene FaYUC11 and application 上海市农业科学院 2017-05-03 CN disclosed
CN-106119113-A For producing the biology of 1,3 butanediols 基因组股份公司 2016-11-16 CN disclosed
CN-102625846-B Organisms for the production of 1, 3-butanediol 基因组股份公司 2016-08-03 CN disclosed
CN-102762735-B Microorganisms producing 1, 4-butanediol, 4-hydroxybutyraldehyde, 4-hydroxybutyryl-COA, putrescine and related compounds and related methods 基因组股份公司 2016-08-03 CN disclosed
CN-105473726-A Keto-isovalerate decarboxylase enzymes and methods of use thereof BUTAMAX(TM) ADVANCED BIOFUELS LLC 2016-04-06 CN disclosed
CN-105441374-A Microorganism for producing 1, 4-butanediol, 4-hydroxybutyraldehyde, 4-maloyl-COA, putrescine and related compound and related method thereof GENOMATICA INC 2016-03-30 CN disclosed
CN-105431520-A 3-hydroxypropionic acid production using recombinant yeast expressing insect aspartate 1-decarboxylase NOVOZYMES AS 2016-03-23 CN disclosed
CN-105209626-A 3-hydroxypropionic acid production by recombinant yeasts NOVOZYMES INC 2015-12-30 CN disclosed
CN-105189764-A Methods of producing 7-carbon chemicals via C1 carbon chain elongation associated with coenzyme B synthesis INVISTA TECH SARL 2015-12-23 CN disclosed
CN-105189770-A Methods of producing 7-carbon chemicals via carbon chain elongation associated with cyclohexane carboxylate synthesis INVISTA TECH SARL 2015-12-23 CN disclosed
EP-2465929-B1 R-HNL random variants and their use for preparing optically pure, sterically hindered cyanohydrins DSM IP ASSETS BV (NL) 2015-12-02 EP disclosed
CN-105051022-A Process and intermediates for the preparation of pregabalin PFIZER IRELAND PHARMACEUTICALS 2015-11-11 CN disclosed
CN-104903455-A Method for biosynthesis of isobutene INVISTA TECH SARL 2015-09-09 CN disclosed
CN-104884629-A Microorganisms and methods for producing fatty alcohols of specific length and related compounds GENOMATICA INC 2015-09-02 CN disclosed
CN-104768560-A Diagnosis and treatment of autism spectrum disorders CALIFORNIA INST OF TECHN 2015-07-08 CN disclosed
CN-104520426-A Biosynthetic pathways, recombinant cells, and methods UNIV MINNESOTA 2015-04-15 CN disclosed
CN-102245780-B Production of branched-chain alcohols by photosynthetic microoraganisms SYNTHETIC GENOMICS INC 2015-03-25 CN disclosed
US-20150005360-A1 PHYTOESTROGEN COMPOSITIONS AND ASSOCIATED METHODS NSE PRODUCTS, INC. (US) 2015-01-01 US disclosed
CN-102317464-B Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks CELEXION, LLC (US) 2014-10-29 CN disclosed
US-8846366-B2 R-hydroxynitrile lyase (R-HNL) random variants and their use for preparing optically pure, sterically hindered cyanohydrins DSM IP ASSETS BV (NL) 2014-09-30 US disclosed
CN-103946383-A Microorganisms and methods for producing olefins GENOMATICA INC 2014-07-23 CN disclosed
CN-103917651-A Eukaryotic organisms and methods for producing 1,3-butanediol GENOMATICA INC 2014-07-09 CN disclosed
CN-103890185-A Microorganisms and methods for producing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol and related alcohols GENOMATICA INC 2014-06-25 CN disclosed
CN-101611141-B Random variants of R-HNL and their use for the preparation of optically pure sterically hindered cyanohydrins DSM IP ASSETS BV 2014-05-07 CN disclosed
EP-2092060-B1 R-HNL RANDOM VARIANTS AND THEIR USE FOR PREPARING OPTICALLY PURE, STERICALLY HINDERED CYANOHYDRINS DSM IP ASSETS BV (NL) 2014-01-22 EP disclosed
CN-103502432-A Compositions and methods for producing 3-hydroxypropionic acid NOVOZYMES INC 2014-01-08 CN disclosed
EP-2141148-B1 INDOLE DERIVATIVE HAVING CPLA2 INHIBITORY ACTIVITY, USE OF THE SAME AND METHOD FOR PRODUCING THE SAME DAIICHI SANKYO CO LTD (JP) 2013-07-03 EP disclosed
CN-102762735-A Microorganisms producing 1, 4-butanediol, 4-hydroxybutyraldehyde, 4-hydroxybutyryl-COA, putrescine and related compounds and related methods GENOMATICA INC 2012-10-31 CN disclosed
US-8293781-B2 Indole derivatives having cPLA2 inhibiting activity and applications and production methods of the same DAIICHI SANKYO COMPANY, LIMITED (JP) 2012-10-23 US disclosed
CN-102625846-A Organisms for the production of 1, 3-butanediol GENOMATICA INC 2012-08-01 CN disclosed
CN-102625845-A Microorganisms and methods for the synergistic production of isopropanol and primary alcohols, glycols and acids GENOMATICA INC 2012-08-01 CN disclosed
EP-2465929-A1 R-HNL random variants and their use for preparing optically pure, sterically hindered cyanohydrins DSM IP Assets B.V. (NL) 2012-06-20 EP disclosed
CN-101321775-B ODCASE inhibitors for the treatment of malaria UNIV HEALTH NETWORK 2012-05-23 CN disclosed
CN-102317464-A From alpha-ketoacid biosynthesizing difunctionality alkane CELEXION LLC 2012-01-11 CN disclosed
CN-102245780-A Production of branched-chain alcohols by photosynthetic microoraganisms SYNTHETIC GENOMICS INC 2011-11-16 CN disclosed
US-20100143986-A1 R-HNL RANDOM VARIANTS AND THEIR USE FOR PREPARING OPTICALLY PURE, STERICALLY HINDERED CYANOHYDRINS DSM IP ASSETS BV (NL) 2010-06-10 US disclosed
US-20100113777-A1 INDOLE DERIVATIVES HAVING cPLA2 INHIBITING ACTIVITY AND APPLICATIONS AND PRODUCTION METHODS OF THE SAME ASUBIO PHARMA CO., LTD. (JP) 2010-05-06 US disclosed
US-20100041110-A1 R-Hydroxynitrile Lyases Having Improved Substrate Acceptance and the Use Thereof DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2010-02-18 US disclosed
EP-2141148-A1 INDOLE DERIVATIVE HAVING CPLA2 INHIBITORY ACTIVITY, USE OF THE SAME AND METHOD FOR PRODUCING THE SAME Asubio Pharma Co., Ltd. (JP) 2010-01-06 EP disclosed
CN-101611141-A Random variants of R-HNL and their use for the preparation of optically pure sterically hindered cyanohydrins DSM IP ASSETS BV (NL) 2009-12-23 CN disclosed
EP-2092060-A1 R-HNL RANDOM VARIANTS AND THEIR USE FOR PREPARING OPTICALLY PURE, STERICALLY HINDERED CYANOHYDRINS DSMIP Assets B.V. (NL) 2009-08-26 EP disclosed
US-7572608-B2 R-hydroxynitrillyases having improved substrate tolerance and the use thereof DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO. KG (AT) 2009-08-11 US disclosed
CN-101495643-A Process for preparing pentamethylene 1,5-diisocyanate BASF SE (DE) 2009-07-29 CN disclosed
EP-1613748-B1 R-HYDROXYNITRILLYASES HAVING IMPROVED SUBSTRATE TOLERANCE AND THE USE THEREOF DSM FINE CHEM AUSTRIA GMBH (AT) 2009-04-15 EP disclosed
US-7514245-B2 Method for producing chiral α-hydroxycarboxylic acids by enzymatic hydrolysis of chiral cyanohydrins DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO. KG (AT) 2009-04-07 US disclosed
EP-1566441-B1 Genes coding for hydroxynitrile lyase, recombinant proteins with hydroxynitrile lyase activity and their use DSM FINE CHEM AUSTRIA GMBH (AT) 2009-02-18 EP disclosed
CN-101321775-A ODCASE inhibitors for the treatment of malaria UNIV HEALTH NETWORK (CA) 2008-12-10 CN disclosed
CN-101297042-A Fermentive production of four carbon alcohols DU PONT (US) 2008-10-29 CN disclosed
US-20080206827-A1 Method for producing chiral a-hydroxycarboxylic crystalline acids DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO. KG (AT) 2008-08-28 US disclosed
US-7390647-B2 Method for producing chiral α-hydroxycarboxylic crystalline acids DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2008-06-24 US disclosed
WO-2008071695-A1 R-HNL RANDOM VARIANTS AND THEIR USE FOR PREPARING OPTICALLY PURE, STERICALLY HINDERED CYANOHYDRINS DSM IP ASSETS BV (NL) 2008-06-19 WO disclosed
CN-100390189-C Production of 2 '-deoxynucleosides and 2' -deoxynucleoside precursors from 2-dehydro-3-deoxy-D-gluconic acid EVOLOGIC S A (FR) 2008-05-28 CN disclosed
CN-101103113-A R-hydroxynitrile lyases having improved substrate acceptance and the use thereof DSM FINE CHEM AUSTRIA GMBH (AT) 2008-01-09 CN disclosed
EP-1838855-A1 R-HYDROXYNITRILE LYASES HAVING IMPROVED SUBSTRATE ACCEPTANCE AND THE USE THEREOF DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2007-10-03 EP disclosed
US-7202075-B2 Isolated protein having hydroxynitrile lyase activity DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2007-04-10 US disclosed
CN-1287154-C Method for detecting or determining virus ADVANCED LIFE SCIENCE INST INC (JP) 2006-11-29 CN disclosed
CN-1832954-A Production of 2 '-deoxynucleosides and 2' -deoxynucleoside precursors from 2-dehydro-3-deoxy-D-gluconic acid EVOLOGIC S A (FR) 2006-09-13 CN disclosed
US-20060199256-A1 Method for producing chiral alpha-hydroxycarboxylic acids by enzymatic hydrolysis of chiral cyanohydrins DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2006-09-07 US disclosed
WO-2006076965-A1 R-HYDROXYNITRILE LYASES HAVING IMPROVED SUBSTRATE ACCEPTANCE AND THE USE THEREOF DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2006-07-27 WO disclosed
EP-0927766-B1 Enzymatic process for the preparation of (S)-cyanhydrines DSM FINE CHEM AUSTRIA GMBH (AT) 2006-06-14 EP disclosed
US-7052885-B2 Process for preparing heterocyclic (R)- and (S)-cyanohydrins DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2006-05-30 US disclosed
US-20060105434-A1 R-hydroxynitrillyases havign improved substrate tolerance and the use thereof DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) 2006-05-18 US disclosed
US-20060099696-A1 Method for Producing Chiral Alpha-Hydroxycarboxylic Crystalline Acids DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2006-05-11 US disclosed
EP-1323830-B1 Process for the preparation of heterocyclic (R)- et (S)-cyanohydrines DSM FINE CHEM AUSTRIA GMBH (AT) 2006-04-26 EP disclosed
EP-1223220-B1 Genes coding for hydroxynitrile lyase, recombinant proteins with hydroxynitrile lyase activity and their use DSM FINE CHEM AUSTRIA GMBH (AT) 2006-03-01 EP disclosed
EP-1566441-A1 Genes coding for hydroxynitrile lyase, recombinant proteins with hydroxynitrile lyase activity and their use DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2005-08-24 EP disclosed
EP-1148042-B1 Method for producing optically and chemically pure (R)- and (S)-hydroxycarboxylic acids DSM FINE CHEM AUSTRIA GMBH (AT) 2005-07-06 EP disclosed
CN-1207569-C Method for assaying virus-containing sample, virus assaying method and diagnostic kit ADVANCED LIFE SCIENCE INST INC (JP) 2005-06-22 CN disclosed
US-20050064552-A1 Genes containing a DNA sequence coding for hydroxynitrile lyase, recombinant proteins derived therefrom and having hydroxynitrile lyase activity, and use thereof DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) 2005-03-24 US disclosed
US-6861243-B2 Genes containing a DNA sequence coding for hydroxynitrile lyase, recombinant proteins derived therefrom and having hydroxynitrile lyase activity, and use thereof DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO. KG (AT) 2005-03-01 US disclosed
WO-2004090124-A2 SEQUENCES ENCODING S-HYDROXYNITRIL LYASES AND THEIR USE IN METHODS FOR THE PRODUCTION OF CYANOHYDRINS BASF AKTIENGESELLSCHAFT (DE) 2004-10-21 WO disclosed
US-6781012-B2 ACID HYDROLYSIS OF THE CORRESPONDING CYANOHYDRIN; EXTRACTION; COOLING DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2004-08-24 US disclosed
EP-1010702-B1 Process for preparing ortho-substituted aryl metal compounds and their conversion with electrophiles MERCK PATENT GMBH (DE) 2004-07-28 EP disclosed
CN-1492231-A Method for detecting or determining virus 株式会社先端生命科学研究所 2004-04-28 CN disclosed
US-6717006-B1 REACTING ALDEHYDE OR KETONE WITH HYDROCYANIC ACID STIRRED AQUEOUS-SOLVENT EMULSION; REDUCED ENZYME AND TIME REQUIREMENTS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2004-04-06 US disclosed
EP-1010703-B1 Process for preparing aryl metal compounds and their conversion with electrophiles MERCK PATENT GMBH (DE) 2004-02-25 EP disclosed
EP-1238094-B1 METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE CYANOHYDRINS USING R-OXYNITRILASE DSM FINE CHEM AUSTRIA GMBH (AT) 2004-02-04 EP disclosed
US-20030129712-A1 Process for preparing heterocyclic (R)- and (S)-cyanohydrins DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) 2003-07-10 US disclosed
EP-1323830-A2 Process for the preparation of heterocyclic (R)- and (S)-cyanohydrines DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2003-07-02 EP disclosed
US-20030119099-A1 Genes containing a DNA sequence coding for hydroxynitrile lyase, recombinant proteins derived therefrom and having hydroxynitrile lyase activity, and use thereof DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) 2003-06-26 US disclosed
EP-1223220-A1 Genes coding for hydroxynitrile lyase, recombinant proteins with hydroxynitrile lyase activity and their use DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2002-07-17 EP disclosed
EP-1223168-A1 Method for the preparation of enantiomerically enriched amino and hydroxyfuranones DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2002-07-17 EP disclosed
US-6417377-B1 Process for preparing enantiomer-enriched amino- and hydroxyfuranones DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2002-07-09 US disclosed
EP-0957083-B1 Process for stabilising cyanhydrines DSM FINE CHEM AUSTRIA GMBH (AT) 2002-04-10 EP disclosed
CN-1330716-A Method for controlling gene expression in bacteria, i.e., Agrobacterium rhizogenes, to improve root nodule development, nitrogen fixation, and plant biomass production G IN E ST R A SOCIETA CONSORTI (IT) 2002-01-09 CN disclosed
US-20010041359-A1 Process for the preparation of optically and chemically highly pure (R) - or (S) -alpha- hydroxycarboxylic acids DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) 2001-11-15 US disclosed
EP-1148042-A2 Method for producing optically and chemically pure (R)- and (S)-hydroxycarboxylic acids DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2001-10-24 EP disclosed
US-6225095-B1 REACTING ALDEHYDE OR KETONE DISSOLVED IN AN ORGANIC, WATER-IMMISCIBLE OR SLIGHTLY MISCIBLE DILUENT, AN AQUEOUS HYDROXYNITRILE LYASE SOLUTION, AND A CYANIDE GROUP DONOR TO FORM AN EMULSION WHICH IS MAINTAINED BY STIRRING DSM FINE CHEMICALS AUSTRIA GMBH (AT) 2001-05-01 US disclosed
US-6207835-B1 DEPROTONATION IN CONTINUOUS FLOW REACTOR MERCK KGAA (DE) 2001-03-27 US disclosed
EP-1010702-A2 Process for preparing ortho-substituted aryl metal compounds and their conversion with electrophiles MERCK PATENT GmbH (DE) 2000-06-21 EP disclosed
EP-1010703-A2 Process for preparing aryl metal compounds and their conversion with electrophiles MERCK PATENT GmbH (DE) 2000-06-21 EP disclosed
US-6031123-A Process for stabilizing cyanohydrins DSM FINE CHEMICALS AUSTRIA GMBH (AT) 2000-02-29 US disclosed
CN-1239548-A Method for detecting or determining viruses TONEN CORP (JP) 1999-12-22 CN disclosed
EP-0957083-A2 Process for stabilising cyanhydrines DSM Fine Chemicals Austria GmbH (AT) 1999-11-17 EP disclosed
EP-0927766-A1 Enzymatic process for the preparation of (S)-cyanhydrines DSM Fine Chemicals Austria GmbH (AT) 1999-07-07 EP disclosed
US-4510315-A CARDIOVASCULAR DISORDERS SANOFI, S.A. (FR) 1985-04-09 US disclosed
EP-0025727-B1 INDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM SANOFI S.A. (FR) 1984-03-28 EP disclosed
US-4404217-A DRUGS ACTIVE ON CARDIOVASCULAR SYSTEM C. M. INDUSTRIES (FR) 1983-09-13 US disclosed
EP-0025727-A1 Indole derivatives, process for their preparation and medicaments containing them SANOFI S.A. (FR) 1981-03-25 EP disclosed
US-4104402-A BRONCHODILATORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1978-08-01 US disclosed
US-4035512-A Aminotetralols TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-07-12 US disclosed
US-4010202-A TREATMENT OF ASTHMA AND ARRHYTHMIA TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-03-01 US disclosed
US-3953442-A ANALGESICS, CENTRAL NERVOUS SYSTEM CLIN MIDY (FR) 1976-04-27 US disclosed
US-3953442-A ANALGESICS, CENTRAL NERVOUS SYSTEM CLIN MIDY (FR) 1976-04-27 US disclosed
US-3933853-A ANALGESICS, TRANQUILIZERS CLIN MIDY (FR) 1976-01-20 US disclosed
US-3933853-A ANALGESICS, TRANQUILIZERS CLIN MIDY (FR) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113777-A1 INDOLE DERIVATIVES HAVING cPLA2 INHIBITING ACTIVITY AND APPLICATIONS AND PRODUCTION METHODS OF THE SAME PLA2G4A, PLA2G2E, PLA2G6 MTNR1A 342/4885MTNR1B 387/4885LOXL2 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.