SCHEMBL13833759

SCHEMBL13833759

O=C(/C=C/c1ccccc1)OCc1ccc(COC(=O)/C=C/c2ccccc2)cc1

nearest known ligand 0.93

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.93
▸ AKR1B10 O60218 7/20 0.79
▸ AKR1B1 P15121 7/20 0.79
▸ CA12 O43570 3/20 0.79
▸ CA4 P22748 3/20 0.79
▸ CA6 P23280 3/20 0.79
▸ CA5A P35218 3/20 0.79
▸ CA7 P43166 3/20 0.79
▸ CA9 Q16790 3/20 0.79
▸ CA14 Q9ULX7 3/20 0.79
▸ CA5B Q9Y2D0 3/20 0.79
▸ TTR P02766 1/20 0.66
▸ HCAR2 Q8TDS4 2/20 0.64
▸ MAOB P27338 1/20 0.59
▸ RAB9A P51151 2/20 0.58
▸ APP P05067 1/20 0.58
▸ ALDH1A1 P00352 1/20 0.56
▸ POLB P06746 1/20 0.56
▸ MET P08581 2/20 0.55
▸ CA1 P00915 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzyl Cinnamate SCHEMBL43213 0.96 LMNA (1.00) LMNAAKR1B10AKR1B1CA12CA4
Benzyl Cinnamate SCHEMBL1871854 0.96 LMNA (1.00) LMNAAKR1B10AKR1B1CA12CA4
Benzyl Cinnamate SCHEMBL901152 0.96 LMNA (1.00) LMNAAKR1B10AKR1B1CA12CA4
Benzyl Cinnamate SCHEMBL43212 0.96 LMNA (1.00) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL22510990 0.95 AKR1B10 (0.88) LMNAAKR1B10AKR1B1CA12CA4
Benzyl Cinnamate SCHEMBL28028350 0.93 LMNA (0.93) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL13552179 0.93 LMNA (0.93) LMNAAKR1B10AKR1B1CA12CA4
Benzyl Cinnamate SCHEMBL30513717 0.92 LMNA (0.90) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL8377990 0.91 LMNA (0.77) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL8377988 0.91 LMNA (0.77) LMNAAKR1B10AKR1B1CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968452-B2 Phase change inks containing crystalline trans-cinnamic diesters and amorphous isosorbide oligomers XEROX CORPORATION (US) 2015-03-03 — — US disclosed
US-8968452-B2 Phase change inks containing crystalline trans-cinnamic diesters and amorphous isosorbide oligomers XEROX CORPORATION (US) 2015-03-03 — — US disclosed
US-8952191-B2 Ester resin compositions XEROX CORPORATION (US) 2015-02-10 — — US disclosed
US-8952191-B2 Ester resin compositions XEROX CORPORATION (US) 2015-02-10 — — US disclosed
US-8936359-B2 Ink compositions incorporating ester resins XEROX CORPORATION (US) 2015-01-20 — — US disclosed
US-8936359-B2 Ink compositions incorporating ester resins XEROX CORPORATION (US) 2015-01-20 — — US disclosed
US-8906150-B2 Phase change inks containing crystalline trans-cinnamic diesters and polyterpene resins XEROX CORPORATION (US) 2014-12-09 — — US disclosed
US-8906150-B2 Phase change inks containing crystalline trans-cinnamic diesters and polyterpene resins XEROX CORPORATION (US) 2014-12-09 — — US disclosed
US-8778069-B2 Phase change inks containing oligomeric rosin esters XEROX CORPORATION (US) 2014-07-15 — — US disclosed
US-8778069-B2 Phase change inks containing oligomeric rosin esters XEROX CORPORATION (US) 2014-07-15 — — US disclosed
US-20140139591-A1 INK COMPOSITIONS INCORPORATING ESTER RESINS XEROX CORPORATION (US) 2014-05-22 — — US disclosed
US-20140137767-A1 Phase Change Inks Containing Oligomeric Rosin Esters XEROX CORPORATION (US) 2014-05-22 — — US disclosed
US-20140137767-A1 Phase Change Inks Containing Oligomeric Rosin Esters XEROX CORPORATION (US) 2014-05-22 — — US disclosed
US-20140139591-A1 INK COMPOSITIONS INCORPORATING ESTER RESINS XEROX CORPORATION (US) 2014-05-22 — — US disclosed
US-20140142335-A1 ESTER RESIN COMPOSITIONS XEROX CORPORATION (US) 2014-05-22 — — US disclosed
US-20130131226-A1 Phase Change Inks Containing Crystalline Trans-Cinnamic Diesters and Polyterpene Resins XEROX CORPORATION (US) 2013-05-23 — — US disclosed
US-20130131226-A1 Phase Change Inks Containing Crystalline Trans-Cinnamic Diesters and Polyterpene Resins XEROX CORPORATION (US) 2013-05-23 — — US disclosed
US-20130032056-A1 Phase Change Inks Containing Crystalline Trans-Cinnamic Diesters and Amorphous Isosorbide Oligomers XEROX CORPORATION (US) 2013-02-07 — — US disclosed
US-20130032056-A1 Phase Change Inks Containing Crystalline Trans-Cinnamic Diesters and Amorphous Isosorbide Oligomers XEROX CORPORATION (US) 2013-02-07 — — US disclosed
WO-2012149604-A1 BIS-THYMINE DERIVATIVES AND PHOTO-REVERSIBLE POLYMERS THEREOF MONASH UNIVERSITY (AU) 2012-11-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140142335-A1 ESTER RESIN COMPOSITIONS ELL, ELOB, ELOC LMNA 2207/4885AKR1B10 1565/4885AKR1B1 2282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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