Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13833769 | 0.86 | PDE4A (0.40) | KDM4EMEN1KMT2A | |
| SCHEMBL13833765 | 0.84 | ALDH1A1 (0.41) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9120180 | 0.83 | PDE4A (0.48) | MAPTKMT2A | |
| SCHEMBL13833770 | 0.82 | MEN1 (0.54) | CREBBPMEN1KMT2A | |
| SCHEMBL8026931 | 0.73 | ALDH1A1 (0.51) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL27386680 | 0.73 | GRIN2D (0.40) | KDM4EALDH1A1MAPTPOLBMCL1 | |
| SCHEMBL9123408 | 0.72 | PDE4A (0.52) | MAPT | |
| SCHEMBL24666582 | 0.71 | KDM4E (0.44) | KDM4EALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL17870783 | 0.71 | KDM4E (0.38) | KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL13833766 | 0.69 | MEN1 (0.55) | KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012149604-A1 | BIS-THYMINE DERIVATIVES AND PHOTO-REVERSIBLE POLYMERS THEREOF | MONASH UNIVERSITY (AU) | 2012-11-08 | — | — | WO | disclosed |