Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13833787 | 0.86 | KDM4E (0.43) | KDM4EMEN1KMT2A | |
| SCHEMBL13833765 | 0.82 | ALDH1A1 (0.41) | KDM4ECNR2TNFMEN1KMT2A | |
| SCHEMBL9120180 | 0.82 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL13833770 | 0.81 | MEN1 (0.54) | TNFMEN1KMT2ALMNA | |
| SCHEMBL8026931 | 0.72 | ALDH1A1 (0.51) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL9123408 | 0.71 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL13724897 | 0.69 | TYMP (0.54) | KMT2ALMNA | |
| SCHEMBL893382 | 0.67 | PTGS1 (0.38) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL7606566 | 0.67 | TRPC5 (0.43) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL8071799 | 0.67 | TRPC5 (0.43) | PDE4APDE4BPDE4CPDE4DKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012149604-A1 | BIS-THYMINE DERIVATIVES AND PHOTO-REVERSIBLE POLYMERS THEREOF | MONASH UNIVERSITY (AU) | 2012-11-08 | — | — | WO | disclosed |