Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13833760 | 0.99 | KAT2B (0.41) | ALDH1A1MEN1KMT2AKAT2BKDM4E | |
| SCHEMBL13833770 | 0.87 | MEN1 (0.54) | MEN1KMT2ATNF | |
| SCHEMBL13833766 | 0.85 | MEN1 (0.55) | ALDH1A1MEN1KMT2AKAT2BKDM4E | |
| SCHEMBL13833787 | 0.84 | KDM4E (0.43) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL13833769 | 0.82 | PDE4A (0.40) | MEN1KMT2AKDM4ETNFCNR2 | |
| SCHEMBL9120180 | 0.79 | PDE4A (0.48) | KMT2ATNFCNR1CNR2TP53 | |
| SCHEMBL14185053 | 0.77 | KMT2A (0.46) | ALDH1A1MEN1KMT2AKAT2BKDM4E | |
| SCHEMBL8026931 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL28651448 | 0.73 | SMN1; SMN2 (0.39) | ALDH1A1MEN1KMT2AKAT2BKDM4E | |
| SCHEMBL2153546 | 0.72 | LMNA (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012149604-A1 | BIS-THYMINE DERIVATIVES AND PHOTO-REVERSIBLE POLYMERS THEREOF | MONASH UNIVERSITY (AU) | 2012-11-08 | — | — | WO | disclosed |