Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 10/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383842 | 0.84 | ALOX5 (0.42) | CASRALOX5 | |
| SCHEMBL1386123 | 0.83 | CASR (0.41) | CASRALOX5SPHK2SPHK1 | |
| SCHEMBL1386007 | 0.81 | MEN1 (0.42) | CASRSPHK2SPHK1 | |
| SCHEMBL3942434 | 0.79 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL1383618 | 0.78 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL1386105 | 0.73 | MEN1 (0.47) | CASRRXFP1 | |
| SCHEMBL1386672 | 0.73 | KMT2A (0.43) | CASRTHRB | |
| SCHEMBL3941835 | 0.73 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL1385344 | 0.73 | CASR (0.54) | CASRTHRBRXFP1 | |
| SCHEMBL1385867 | 0.73 | CASR (0.59) | CASRTHRBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |