Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 7/20 | 0.55 |
| ▸ | RIPK1 | Q13546 | 8/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385867 | 0.94 | CASR (0.59) | CASRRIPK1THRB | |
| SCHEMBL1386100 | 0.92 | CASR (0.56) | CASRRIPK1THRB | |
| SCHEMBL1386625 | 0.90 | CASR (0.59) | CASRRIPK1THRBSIGMAR1 | |
| SCHEMBL1383223 | 0.89 | CASR (0.48) | CASRRIPK1TMEM97SIGMAR1 | |
| SCHEMBL1383373 | 0.89 | CASR (0.55) | CASRTHRBTMEM97SIGMAR1 | |
| SCHEMBL1383335 | 0.86 | CASR (0.54) | CASRRIPK1THRB | |
| SCHEMBL1385344 | 0.86 | CASR (0.54) | CASRTHRB | |
| SCHEMBL1383579 | 0.85 | CASR (0.55) | CASRTHRB | |
| SCHEMBL1384253 | 0.84 | CASR (0.51) | CASRTHRBLMNA | |
| SCHEMBL1385738 | 0.81 | CASR (0.46) | CASRTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |