Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 8/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385867 | 0.91 | CASR (0.59) | CASRTHRBRXFP1 | |
| SCHEMBL1386100 | 0.90 | CASR (0.56) | CASRTHRBRXFP1 | |
| SCHEMBL1385847 | 0.89 | CASR (0.55) | CASRSIGMAR1TMEM97THRB | |
| SCHEMBL1386625 | 0.87 | CASR (0.59) | CASRSIGMAR1THRB | |
| SCHEMBL1385344 | 0.84 | CASR (0.54) | CASRTHRBRXFP1 | |
| SCHEMBL1383335 | 0.84 | CASR (0.54) | CASRTHRBRXFP1 | |
| SCHEMBL1383579 | 0.83 | CASR (0.55) | CASRTHRBRXFP1 | |
| SCHEMBL1384253 | 0.82 | CASR (0.51) | CASRTHRB | |
| SCHEMBL1383223 | 0.79 | CASR (0.48) | CASRSIGMAR1TMEM97 | |
| SCHEMBL3945754 | 0.78 | CASR (0.41) | CASRSIGMAR1TMEM97NTRK1NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |