Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | OXTR | P30559 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13835559 | 0.89 | HTR1F (0.45) | ALDH1A1SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL13835132 | 0.89 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL14850246 | 0.88 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL13968275 | 0.86 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL13836482 | 0.85 | KDM4E (0.39) | ALDH1A1SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL15073412 | 0.83 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL299503 | 0.83 | GPR6 (0.39) | ALDH1A1SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL298947 | 0.82 | KMT2A (0.45) | SMN1; SMN2LMNARAB9ANPSR1MAPT | |
| SCHEMBL13968284 | 0.82 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL297521 | 0.82 | RXFP1 (0.45) | ALDH1A1SMN1; SMN2NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3339286-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-27 | — | — | EP | disclosed |
| EP-2427426-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-07 | — | — | EP | disclosed |
| WO-2013092942-A1 | USE OF AMINOBENZAMIDE DERIVATIVES FOR CONTROLLING ANIMAL PARASITES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-06-27 | — | — | WO | disclosed |
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, BCHE | ALDH1A1 331/4885SMN1; SMN2 1116/4885NPC1 918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.