SCHEMBL1383783

SCHEMBL1383783

O=C(NCCC(O)c1ccc(O)c(O)c1)c1cnc(NCc2ccccc2)nc1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CASR P41180 13/20 0.50
THRB P10828 2/20 0.46
STAT6 P42226 3/20 0.42
RXFP1 Q9HBX9 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1384031 0.78 CASR (0.53) CASR
SCHEMBL1383520 0.74 THRB (0.52) CASRTHRBRXFP1
SCHEMBL3944707 0.74 CCNE2 (0.39) CASRSTAT6RXFP1
SCHEMBL3442955 0.73 ATM (0.57) CASRTHRBSTAT6
SCHEMBL1383382 0.72 CASR (0.46) CASRTHRBRXFP1
SCHEMBL1385738 0.72 CASR (0.46) CASR
SCHEMBL1386100 0.72 CASR (0.56) CASRTHRBRXFP1
SCHEMBL1385344 0.72 CASR (0.54) CASRTHRBRXFP1
SCHEMBL1385867 0.71 CASR (0.59) CASRTHRBRXFP1
SCHEMBL1386304 0.70 SLC16A3 (0.41) CASRTHRBSTAT6RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4825686-B2 2011-11-30 JP claimed