Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | CASR | P41180 | 7/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383650 | 0.89 | LMNA (0.43) | THRBCASRRXFP1RAB9AHDAC3 | |
| SCHEMBL1383227 | 0.87 | ALDH1A1 (0.42) | THRBCASRRXFP1RAB9AMAPK1 | |
| SCHEMBL1384191 | 0.82 | CASR (0.55) | THRBCASRRXFP1 | |
| SCHEMBL3442955 | 0.77 | ATM (0.57) | THRBCASRRAB9ANPSR1ATM | |
| SCHEMBL1383783 | 0.74 | CASR (0.50) | THRBCASRRXFP1 | |
| SCHEMBL3943937 | 0.73 | NPY5R (0.47) | CASRRAB9ANPSR1ATM | |
| SCHEMBL1384551 | 0.71 | CASR (0.46) | CASRRAB9A | |
| SCHEMBL1386304 | 0.70 | SLC16A3 (0.41) | THRBCASRRXFP1RAB9ANPSR1 | |
| SCHEMBL1385867 | 0.67 | CASR (0.59) | THRBCASRRXFP1 | |
| SCHEMBL3443239 | 0.67 | HDAC3 (0.53) | THRBCASRATMHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |