Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CD22 | P20273 | 1/20 | 0.30 |
| ▸ | MAG | P20916 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13839169 | 0.89 | BMP1 (0.33) | CD22 | |
| SCHEMBL31695023 | 0.88 | LMNA (0.34) | KMT2ACD22MAG | |
| SCHEMBL14403193 | 0.79 | CASP3 (0.31) | CASP3 | |
| SCHEMBL31502359 | 0.76 | CD22 (0.33) | CD22MAG | |
| SCHEMBL16326647 | 0.75 | TNF (0.34) | TNFKMT2AMAG | |
| SCHEMBL13402483 | 0.75 | LMNA (0.34) | KMT2AMAG | |
| SCHEMBL31695092 | 0.75 | KLK7 (0.32) | — | |
| SCHEMBL13949943 | 0.75 | LMNA (0.35) | KMT2A | |
| SCHEMBL17300143 | 0.75 | NANP (0.37) | — | |
| SCHEMBL14268526 | 0.74 | METAP2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7527934-B2 | Labeled substrate conjugates for identifying enzyme inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-05-05 | — | — | US | disclosed |