Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13840445 | 0.76 | GNRHR (0.45) | NPY5RRORCPTGDR2P2RX3MEN1 | |
| SCHEMBL13840435 | 0.72 | KDM4E (0.70) | NPY5RRORCKDM4EMEN1USP2 | |
| SCHEMBL6753270 | 0.70 | PTGDR2 (0.47) | NPY5RRORCPTGDR2P2RX3KDM4E | |
| SCHEMBL10113681 | 0.66 | KDM4E (0.66) | NPY5RRORCKDM4EMEN1USP2 | |
| Hydrochloric Acid SCHEMBL513574 | 0.66 | NPY5R (0.49) | NPY5RRORCPTGDR2P2RX3 | |
| SCHEMBL10113895 | 0.65 | MAPK1 (0.52) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13840437 | 0.65 | MAPT (0.50) | KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL2601904 | 0.64 | ALDH1A1 (0.43) | KDM4EUSP2ALDH1A1 | |
| SCHEMBL4726943 | 0.64 | NPY5R (1.00) | NPY5RKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL14596559 | 0.64 | ALDH1A1 (0.47) | USP2KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534892-B2 | Sulfonamide compound | SHIONOGI & CO., LTD. (JP) | 2009-05-19 | — | — | US | disclosed |
| US-7534892-B2 | Sulfonamide compound | SHIONOGI & CO., LTD. (JP) | 2009-05-19 | — | — | US | disclosed |
| US-20070287710-A1 | Piperidinediyl-containing sulfonamide; NPY Y5 receptor antagonist activity; antiobesity agent or anorectic agent | SHIONOGI & CO., LTD. (JP) | 2007-12-13 | — | — | US | disclosed |
| US-20070287710-A1 | Piperidinediyl-containing sulfonamide; NPY Y5 receptor antagonist activity; antiobesity agent or anorectic agent | SHIONOGI & CO., LTD. (JP) | 2007-12-13 | — | — | US | disclosed |
| EP-1760073-A1 | SULFONAMIDE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2007-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287710-A1 | Piperidinediyl-containing sulfonamide; NPY Y5 receptor antagonist activity; antiobesity agent or anorectic agent | NPY5R, NPY1R, NPY2R | NPY5R 1/4885RORC 1670/4885PTGDR2 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.