Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4174366 | 0.72 | NPY5R (0.46) | ALDH1A1GAAMEN1KMT2ALMNA | |
| SCHEMBL13840449 | 0.70 | NPY5R (0.46) | PTGDR2ALDH1A1MEN1KMT2AP2RX3 | |
| SCHEMBL3386295 | 0.70 | ALDH1A1 (0.52) | ALDH1A1GAAMEN1KMT2ALMNA | |
| SCHEMBL13840445 | 0.69 | GNRHR (0.45) | PTGDR2GAAMEN1KMT2AP2RX3 | |
| SCHEMBL6754538 | 0.68 | HTR6 (0.45) | PTGDR2MEN1KMT2AP2RX3LMNA | |
| SCHEMBL16000906 | 0.67 | ALDH1A1 (0.64) | ALDH1A1GAAMEN1KMT2ALMNA | |
| SCHEMBL1013517 | 0.67 | CYP1A2 (0.65) | ALDH1A1GAAMEN1KMT2ALMNA | |
| SCHEMBL15890231 | 0.67 | NPC1 (0.64) | ALDH1A1GAAMEN1KMT2ATP53 | |
| SCHEMBL29791442 | 0.67 | NPC1 (0.64) | ALDH1A1GAAMEN1KMT2ATP53 | |
| SCHEMBL8063648 | 0.66 | ALDH1A1 (0.82) | ALDH1A1GAAMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713473-B1 | 6-CARBAMATE-1,2,3,4-TETRAHYDROCARBAZOLE DERIVATIVES; AFFINITY FOR NEUROPEPTIDE Y RECEPTORS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-03-30 | — | — | US | disclosed |
| EP-1184373-A1 | TRICYCLIC COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-03-06 | — | — | EP | disclosed |