Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 13/20 | 0.56 |
| ▸ | GNPAT | O15228 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577588 | 1.00 | NOD1 (0.56) | NOD1GNPATSLC6A5FOLH1RIMKLA | |
| SCHEMBL28378530 | 0.88 | NOD1 (0.59) | NOD1GNPATSLC6A5FOLH1RIMKLA | |
| SCHEMBL1895761 | 0.87 | NOD1 (0.73) | NOD1SLC6A5 | |
| SCHEMBL1895758 | 0.87 | NOD1 (0.73) | NOD1SLC6A5 | |
| SCHEMBL133962 | 0.87 | NOD1 (0.47) | NOD1GNPATSLC6A5FOLH1RIMKLA | |
| SCHEMBL3161332 | 0.87 | NOD1 (0.47) | NOD1GNPATSLC6A5FOLH1RIMKLA | |
| SCHEMBL22996019 | 0.86 | NOD1 (0.77) | NOD1SLC6A5 | |
| SCHEMBL132483 | 0.86 | NOD1 (0.77) | NOD1SLC6A5 | |
| SCHEMBL17941648 | 0.86 | NOD1 (0.77) | NOD1SLC6A5 | |
| SCHEMBL5122358 | 0.86 | NOD1 (0.77) | NOD1SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730197-B1 | METHODS FOR INDUCING AUTOLYSIS IN INFECTIOUS BACTERIA | HAPTOGEN LTD (GB) | 2012-03-07 | — | — | EP | claimed |
| EP-0994961-B1 | HOMOSERINE LACTONES BIOFILM REGULATING COMPOUNDS AND THEIR METHODS OF USE | UNIV MONTANA STATE (US) | 2006-10-18 | — | — | EP | claimed |
| US-20040180829-A1 | Compounds and methods for regulating bacterial growth and pathogenesis | QUOREX PHARMACEUTICALS, INC. | 2004-09-16 | — | — | US | claimed |
| US-20040097402-A1 | COMPOUNDS AND METHODS FOR REGULATING BACTERIAL GROWTH AND PATHOGENESIS | NATIONAL SCIENCE FOUNDATION | 2004-05-20 | — | — | US | claimed |
| CN-117326681-A | Treatment method for improving denitrification performance of activated sludge process at low temperature | 四川大学 | 2024-01-02 | — | — | CN | disclosed |
| CN-113322269-B | Biosensor based on bacterial population density sensing protein LuxR and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-08-09 | — | — | CN | disclosed |
| US-11318218-B2 | Targeted enzymatic degradation of quorum-sensing peptides | KCI LICENSING, INC. (US) | 2022-05-03 | — | — | US | disclosed |
| CN-113322269-A | Biosensor based on bacterial population density sensing protein LuxR and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-08-31 | — | — | CN | disclosed |
| CN-106318990-B | Preparation for accelerating methane oxidation of refuse landfill and preparation method and application thereof | 浙江工商大学 | 2020-04-10 | — | — | CN | disclosed |
| US-20190298872-A1 | TARGETED ENZYMATIC DEGRADATION OF QUORUM-SENSING PEPTIDES | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2019-10-03 | — | — | US | disclosed |
| US-10369240-B2 | Targeted enzymatic degradation of quorum-sensing peptides | KCI LICENSING, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180064834-A1 | Targeted Enzymatic Degradation Of Quorum-Sensing Peptides | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2018-03-08 | — | — | US | disclosed |
| US-20050009869-A1 | Novel autoinducer molecules and uses therefor | NATIONAL SCIENCE FOUNDATION | 2005-01-13 | — | — | US | disclosed |
| WO-2004075874-A1 | METHOD FOR TREATMENT AND PREVENTION OF ACUTE AND CHRONIC PSEUDOMONAS AERUGINOSA AIRWAY INFECTIONS WITH INHALABLE MACROLIDES | ANBICS PATENTS-LICENCES AG (CH) | 2004-09-10 | — | — | WO | disclosed |
| US-6777223-B2 | Contacting with acylases and a carrier to degrade a lactone such as an N-acyl-L-homoserine lactone produced by one or more microorganisms | NOVOZYMES BIOTECH, INC. | 2004-08-17 | — | — | US | disclosed |
| US-20040109852-A1 | METHODS FOR ELIMINATING THE FORMATION OF BIOFILM | NOVOZYMES BIOTECH, INC. (US) | 2004-06-10 | — | — | US | disclosed |
| US-6723321-B2 | MODULATION OF LYASE ACTIVITY; OBTAIN SAMPLE CONTAINING LYASE, INCUBATE WITH SUBSTRATE AND MODULATOR, MONITOR ADJUSTMENT IN BINDING OF SUBSTRATE TO LYASE, ADJUSTMENT IN BINDING INDICATES MODULATOR | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2004-04-20 | — | — | US | disclosed |
| WO-2004002976-A1 | DISRUPTION OF PQS SYNTHESIS USING PRECURSOR ANALOGS | EAST CAROLINA UNIVERSITY (US) | 2004-01-08 | — | — | WO | disclosed |
| US-20040002130-A1 | Disruption of PQS synthesis using precursor analogs | EAST CAROLINA UNIVERSITY | 2004-01-01 | — | — | US | disclosed |
| WO-2001098214-A1 | METHODS FOR ELIMINATING THE FORMATION OF BIOFILM | NOVOZYMES BIOTECH, INC. (US) | 2001-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180829-A1 | Compounds and methods for regulating bacterial growth and pathogenesis | BLVRB, BMPR2, ANTXR2 | NOD1 127/4885GNPAT 62/4885SLC6A5 2828/4885 |
| US-20040097402-A1 | COMPOUNDS AND METHODS FOR REGULATING BACTERIAL GROWTH AND PATHOGENESIS | BLVRB, BMPR2, ANTXR2 | NOD1 127/4885GNPAT 62/4885SLC6A5 2828/4885 |
| US-20050009869-A1 | Novel autoinducer molecules and uses therefor | QARS1, PGLS, SQLE | NOD1 272/4885GNPAT 104/4885SLC6A5 3212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.