SCHEMBL1895758

SCHEMBL1895758

CCCCCC(=O)N[C@@H](CCO)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 12/20 0.73
SLC6A5 Q9Y345 2/20 0.58
FAAH O00519 2/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
MAPK1 P28482 1/20 0.53
PLA2G2C Q5R387 1/20 0.51
EPHX2 P34913 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1895761 1.00 NOD1 (0.73) NOD1SLC6A5FAAHMEN1KMT2A
SCHEMBL22996019 0.98 NOD1 (0.77) NOD1SLC6A5FAAHMEN1KMT2A
SCHEMBL131586 0.98 NOD1 (0.77) NOD1SLC6A5FAAHMEN1KMT2A
SCHEMBL17941649 0.98 NOD1 (0.77) NOD1SLC6A5FAAHMEN1KMT2A
SCHEMBL9829340 0.98 NOD1 (0.77) NOD1SLC6A5FAAHMEN1KMT2A
SCHEMBL132483 0.98 NOD1 (0.77) NOD1SLC6A5FAAHMEN1KMT2A
SCHEMBL17941648 0.98 NOD1 (0.77) NOD1SLC6A5FAAHMEN1KMT2A
SCHEMBL5122358 0.98 NOD1 (0.77) NOD1SLC6A5FAAHMEN1KMT2A
SCHEMBL9829330 0.98 NOD1 (0.77) NOD1SLC6A5FAAHMEN1KMT2A
SCHEMBL5888062 0.98 NOD1 (0.77) NOD1SLC6A5FAAHMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104673856-B A kind of fermentation process for improving biological flocculant active component polysaccharides yield 哈尔滨工业大学 2018-04-20 CN claimed
CN-117865342-A Method for efficiently cultivating anaerobic ammonia oxidation granular sludge by utilizing effluent of anaerobic ammonia oxidation reactor 同济大学 2024-04-12 CN disclosed
CN-115161228-B Quorum sensing sudden sterilization and culture method thereof, and biofouling control method for landfill leachate drainage system 北京大学深圳研究生院 2024-03-15 CN disclosed
CN-115367862-B Preparation and application of signal molecule modified sponge ceramic-based biofilm carrier 华南理工大学 2023-11-24 CN disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
CN-106318990-B Preparation for accelerating methane oxidation of refuse landfill and preparation method and application thereof 浙江工商大学 2020-04-10 CN disclosed
WO-2018204764-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION (US) 2018-11-08 WO disclosed
CN-104673856-B A kind of fermentation process for improving biological flocculant active component polysaccharides yield 哈尔滨工业大学 2018-04-20 CN disclosed
CN-104673856-B A kind of fermentation process for improving biological flocculant active component polysaccharides yield 哈尔滨工业大学 2018-04-20 CN disclosed
EP-3024470-A1 ADDITIVE FOR ANIMAL FEED, FOODSTUFFS, DRINKING WATER OR PHARMACEUTICAL PREPARATIONS Erber Aktiengesellschaft (AT) 2016-06-01 EP disclosed
US-20100021942-A1 Cell-free expression system for the detection of bacterial biofilms FREEMONT PAUL 2010-01-28 US disclosed
US-7442798-B2 Quinone-indicator antibiotics, particularly2-heptyl-3-hydroxy-4-quinolone, and analogs; regulating the expression of a bacterial gene; modulating bacteria quorum sensing signaling THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2008-10-28 US disclosed
EP-1834645-A1 Autoinducer synthase modulating compounds and uses therefor UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2007-09-19 EP disclosed
EP-1100513-B1 METHOD FOR PRODUCING AUTOINDUCER SYNTHASE UNIV IOWA RES FOUND (US) 2007-03-21 EP disclosed
US-20070010477-A1 Acyl homoserine lactones for inhibition of cell growth NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-01-11 US disclosed
WO-2006110531-A2 ACYL HOMOSERINE LACTONES FOR INHIBITION OF CELL GROWTH HEALTH RESEARCH INC. (US) 2006-10-19 WO disclosed
US-20050227345-A1 Quorum sensing signaling in bacteria AURORA BIOSCIENCES CORPORATION (US) 2005-10-13 US disclosed
US-6855513-B1 Quorum sensing signaling in bacteria UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2005-02-15 US disclosed
US-20050009869-A1 Novel autoinducer molecules and uses therefor NATIONAL SCIENCE FOUNDATION 2005-01-13 US disclosed
US-6723321-B2 MODULATION OF LYASE ACTIVITY; OBTAIN SAMPLE CONTAINING LYASE, INCUBATE WITH SUBSTRATE AND MODULATOR, MONITOR ADJUSTMENT IN BINDING OF SUBSTRATE TO LYASE, ADJUSTMENT IN BINDING INDICATES MODULATOR THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2004-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070010477-A1 Acyl homoserine lactones for inhibition of cell growth AHCYL1, HCCS, ACSL1 NOD1 3321/4885SLC6A5 2274/4885FAAH 263/4885
US-20050227345-A1 Quorum sensing signaling in bacteria PGLS, Q6ZSR9, FDPS NOD1 1892/4885SLC6A5 2123/4885FAAH 1802/4885
US-20050009869-A1 Novel autoinducer molecules and uses therefor QARS1, PGLS, SQLE NOD1 272/4885SLC6A5 3212/4885FAAH 1450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.