Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | AHR | P35869 | 1/20 | 0.69 |
| ▸ | CASP6 | P55212 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 8/20 | 0.66 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.66 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12326646 | 0.84 | RAB9A (0.72) | RAB9AMEN1KMT2ALMNAPOLB | |
| SCHEMBL13959573 | 0.84 | RAB9A (0.76) | RAB9AMEN1KMT2ALMNAPOLB | |
| SCHEMBL2425706 | 0.83 | RAB9A (0.86) | RAB9AMEN1KMT2ALMNAPOLB | |
| SCHEMBL14105126 | 0.83 | RAB9A (0.67) | RAB9AMEN1KMT2ALMNAPOLB | |
| SCHEMBL3969164 | 0.82 | MEN1 (0.50) | RAB9AMEN1KMT2ALMNAPOLB | |
| SCHEMBL12326650 | 0.82 | RAB9A (0.76) | RAB9AMEN1KMT2ALMNAPOLB | |
| SCHEMBL12325958 | 0.82 | RAB9A (0.72) | RAB9AMEN1KMT2ALMNAPOLB | |
| SCHEMBL2423434 | 0.82 | RAB9A (1.00) | RAB9AMEN1KMT2ALMNAPOLB | |
| SCHEMBL2421809 | 0.82 | LMNA (0.83) | RAB9AMEN1KMT2ALMNAPOLB | |
| SCHEMBL13856816 | 0.82 | LMNA (0.76) | RAB9AMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110306611-A1 | Transcription factor modulating compounds and methods of use thereof | PARATEK PHARMACEUTICALS, INC. (US) | 2011-12-15 | — | — | US | disclosed |
| US-20090131481-A1 | Transcription Factor Modulating Compounds and Methods of Use Thereof | PARATEK PHARMACEUTICALS, INC. (US) | 2009-05-21 | — | — | US | disclosed |
| US-7405235-B2 | Transcription factor modulating compounds and methods of use thereof | PARATEK PHARMACEUTICALS, INC. (US) | 2008-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306611-A1 | Transcription factor modulating compounds and methods of use thereof | JUN, CREBBP, TFEB | RAB9A 4067/4885MEN1 4225/4885KMT2A 806/4885 |
| US-20090131481-A1 | Transcription Factor Modulating Compounds and Methods of Use Thereof | CREBBP, JUN, IRF3 | RAB9A 3873/4885MEN1 4383/4885KMT2A 929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.