Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44636 | 0.54 | TP53 (0.43) | — | |
| SCHEMBL14758396 | 0.54 | TP53 (0.56) | — | |
| SCHEMBL21165326 | 0.53 | CA2 (0.66) | PTGS2 | |
| SCHEMBL4033353 | 0.52 | HTR1A (0.42) | PTGS2 | |
| SCHEMBL14508573 | 0.52 | EPHX2 (0.46) | — | |
| SCHEMBL44571 | 0.51 | NOTUM (0.47) | — | |
| SCHEMBL1118359 | 0.51 | GPR119 (0.48) | — | |
| SCHEMBL12997562 | 0.50 | SMN1; SMN2 (0.57) | — | |
| SCHEMBL9283676 | 0.50 | CA1 (0.54) | — | |
| SCHEMBL3930628 | 0.50 | EPHX2 (0.44) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009059162-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA ENTERPRISES LIMITED (BS) | 2009-05-07 | — | — | WO | disclosed |