Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18573951 | 0.88 | SMN1; SMN2 (0.47) | TPSAB1ALDH1A1PRSS1SMN1; SMN2NUDT1 | |
| SCHEMBL15483861 | 0.86 | ALDH1A1 (0.49) | LMNAALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL18573848 | 0.85 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2NUDT1HDAC1HDAC6 | |
| SCHEMBL15483592 | 0.83 | ALDH1A1 (0.44) | LMNAALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL15483629 | 0.83 | ALDH1A1 (0.44) | LMNAALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL23481321 | 0.82 | CA1 (0.45) | ALDH1A1GAASMN1; SMN2NUDT1HDAC1 | |
| SCHEMBL20434695 | 0.82 | ERCC1 (0.44) | TPSAB1ALDH1A1PRSS1SMN1; SMN2NUDT1 | |
| SCHEMBL2748645 | 0.82 | PIN1 (0.57) | ALDH1A1SMN1; SMN2NUDT1HDAC1HDAC6 | |
| SCHEMBL23764904 | 0.80 | NUDT1 (0.52) | ALDH1A1SMN1; SMN2NUDT1RAB9AMEN1 | |
| SCHEMBL15483836 | 0.79 | ALDH1A1 (0.41) | LMNAALDH1A1HPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060065-A1 | METHOD OF QUANTIFYING TRANSIENT INTERACTIONS BETWEEN PROTEINS | COVALYS BIOSCIENCES AG (CH) | 2009-05-14 | — | — | WO | disclosed |