Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | GUSB | P08236 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4830001 | 0.81 | L3MBTL1 (0.55) | L3MBTL1NPC1GUSBMAPTLMNA | |
| SCHEMBL4825454 | 0.81 | L3MBTL1 (0.58) | L3MBTL1NPC1GUSBMAPTLMNA | |
| SCHEMBL4828176 | 0.81 | L3MBTL1 (0.58) | L3MBTL1NPC1GUSBMAPTLMNA | |
| Bromide SCHEMBL3980221 | 0.81 | L3MBTL1 (0.54) | L3MBTL1NPC1GUSBMAPTLMNA | |
| SCHEMBL4633311 | 0.79 | TSHR (0.67) | L3MBTL1NPC1GUSBMAPTLMNA | |
| SCHEMBL13845817 | 0.79 | HTT (0.52) | L3MBTL1NPC1GUSBMAPTLMNA | |
| SCHEMBL10032067 | 0.79 | NPC1 (0.71) | L3MBTL1NPC1GUSBMAPTLMNA | |
| SCHEMBL31673809 | 0.77 | LMNA (0.73) | L3MBTL1NPC1GUSBMAPTLMNA | |
| SCHEMBL15101603 | 0.77 | LMNA (0.73) | L3MBTL1NPC1GUSBMAPTLMNA | |
| SCHEMBL1061819 | 0.74 | LMNA (0.65) | L3MBTL1NPC1GUSBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063364-A2 | MODULATORS OF UROTENSIN RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS INC. (US) | 2009-05-22 | — | — | WO | disclosed |