Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.43 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13846315 | 0.81 | KMT2A (0.47) | CES2CES1CYP2D6CYP1A2PKM | |
| SCHEMBL280401 | 0.81 | MMP8 (0.56) | CES2CES1SMN1; SMN2KMT2ASLC6A3 | |
| SCHEMBL15898020 | 0.79 | CES2 (0.54) | CES2CES1SMN1; SMN2KMT2ASLC6A3 | |
| SCHEMBL19086397 | 0.79 | CES2 (0.53) | CES2CES1CYP2D6CYP1A2PKM | |
| Ammonia Solution, Strong SCHEMBL28259601 | 0.79 | MMP8 (0.54) | CES2CES1SMN1; SMN2KMT2ASLC6A3 | |
| SCHEMBL10691190 | 0.79 | CES2 (0.54) | CES2CES1SMN1; SMN2KMT2ASLC6A3 | |
| SCHEMBL1275430 | 0.78 | LMNA (0.54) | CES2CES1CYP2D6CYP1A2PKM | |
| SCHEMBL2419442 | 0.78 | LMNA (0.53) | CES2CES1CYP2D6CYP1A2SMN1; SMN2 | |
| SCHEMBL17738787 | 0.78 | CES2 (0.61) | CES2CES1CYP2D6CYP1A2PKM | |
| SCHEMBL27317113 | 0.77 | CYP1A2 (0.46) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124760-A1 | POLYOLEFIN HYBRID POLYMER AND METHOD FOR MANUFACTURING THE SAME | MITSUI CHEMICALS, INC. (JP) | 2009-05-14 | — | — | US | disclosed |