Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13293923 | 0.79 | MMP3 (0.35) | — | |
| SCHEMBL13293354 | 0.71 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL12373068 | 0.67 | KCNH2 (0.47) | KCNH2DRD2 | |
| SCHEMBL16062587 | 0.67 | HTR1B (0.45) | KCNH2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL25728442 | 0.65 | PTPN1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL25233630 | 0.64 | PTPN1 (0.38) | — | |
| SCHEMBL9638565 | 0.62 | CYP1A2 (0.52) | KCNH2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL12373075 | 0.61 | KCNH2 (0.50) | KCNH2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL139611 | 0.60 | HDAC8 (0.50) | — | |
| SCHEMBL139848 | 0.60 | HDAC8 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121371-B1 | NUCLEOTIDE COMPOUNDS INCLUDING A RIGID LINKER | APPLIED BIOSYSTEMS LLC (US) | 2009-05-27 | — | — | EP | disclosed |