Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.34 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL11190535 | 0.83 | HDAC8 (0.38) | CYP1A1CYP1A2CYP1B1MCHR1KEAP1 | |
| SCHEMBL9209153 | 0.77 | KCNH2 (0.41) | KCNH2HTTL3MBTL1LMNAMMP2 | |
| SCHEMBL5243364 | 0.76 | NPSR1 (0.53) | KCNH2HTTLMNAMMP2MMP12 | |
| SCHEMBL2229991 | 0.73 | GABRP (0.41) | KCNH2HTTL3MBTL1LMNAKDM4E | |
| SCHEMBL10984566 | 0.72 | NQO1 (0.58) | KDM4ECYP1A2NPSR1GAA | |
| SCHEMBL9638565 | 0.72 | CYP1A2 (0.52) | KCNH2MMP2MMP12CYP1A1CYP1A2 | |
| SCHEMBL13847091 | 0.71 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL139611 | 0.69 | HDAC8 (0.50) | CYP1A1CYP1A2CYP1B1KEAP1HDAC8 | |
| SCHEMBL139848 | 0.69 | HDAC8 (0.50) | CYP1A1CYP1A2CYP1B1KEAP1HDAC8 | |
| SCHEMBL3016789 | 0.68 | HDAC8 (0.35) | KCNH2HTTL3MBTL1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2202238-A1 | Nucleotide Compounds including a rigid linker | Applied Biosystems, LLC (US) | 2010-06-30 | — | — | EP | disclosed |