Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23895391 | 0.73 | ALDH1A1 (0.46) | TYMPHPGDHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL4982004 | 0.70 | HPGD (0.43) | HPGDHSD17B10ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL3436472 | 0.70 | ADRA1B (0.50) | GAALMNA | |
| SCHEMBL18292984 | 0.68 | HPGD (0.39) | TYMPHPGDHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL14333961 | 0.67 | HPGD (0.43) | TYMPHPGDHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL14123251 | 0.66 | TYMP (0.55) | TYMPHSD17B10ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL20826808 | 0.66 | HPGD (0.36) | TYMPHPGDHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL30091603 | 0.66 | HPGD (0.45) | HPGDHSD17B10ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL7278898 | 0.66 | ALOX15 (0.76) | HPGDHSD17B10ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL14123129 | 0.64 | TYMP (0.46) | TYMPHPGDHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159808-A1 | USE OF COMPOUND APREPITANT IN PREPARATION OF DRUG FOR PREVENTION OR TREATMENT OF AFRICAN SWINE FEVER | 中国农业科学院兰州兽医研究所 | 2023-08-31 | — | — | WO | disclosed |
| WO-2019005830-A1 | NANOSOME FORMULATIONS OF APREPITANT AND METHODS AND APPLICATIONS THEREOF | FORDOZ PHARMA CORP. (US) | 2019-01-03 | — | — | WO | disclosed |
| EP-2837624-B1 | 4-SUBSTITUENT-2-HYDROXYLMORPHOLINE-3-ONE AND PREPARATION METHOD THEREOF | ZHEJIANG HISUN PHARM CO LTD (CN) | 2018-06-27 | — | — | EP | disclosed |
| WO-2009067233-A1 | BETA CARBOLINES AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | WO | disclosed |