Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848300 | 0.83 | HDAC1 (0.36) | HSP90AB1CACNA1GCACNA1HCACNA1IHDAC1 | |
| SCHEMBL13848069 | 0.82 | HSP90AB1 (0.45) | MAPTKDM4EALDH1A1HTTLMNA | |
| SCHEMBL13848415 | 0.79 | ALDH1A1 (0.36) | RXRAKDM4EALDH1A1HTTTP53 | |
| SCHEMBL13848381 | 0.79 | RXRA (0.41) | RXRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13848295 | 0.77 | HPGD (0.48) | MAPTKDM4EALDH1A1TP53LMNA | |
| SCHEMBL13848413 | 0.70 | HSP90AA1 (0.52) | MAPTKDM4EALDH1A1SMN1; SMN2HSP90AB1 | |
| SCHEMBL4065120 | 0.70 | HSP90AB1 (0.41) | MAPTALDH1A1SMN1; SMN2HSP90AB1 | |
| SCHEMBL12589168 | 0.70 | HSP90AB1 (0.37) | MAPTRXRAKDM4EALDH1A1TP53 | |
| SCHEMBL17948632 | 0.69 | HSP90AB1 (0.40) | HSP90AB1 | |
| SCHEMBL13848452 | 0.68 | MAPK14 (0.37) | RXRATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |