Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848381 | 0.89 | RXRA (0.41) | ALDH1A1RXRAL3MBTL1MEN1KMT2A | |
| SCHEMBL4065989 | 0.84 | POLB (0.39) | KMT2ATSHRHPGDHSD17B10AAK1 | |
| SCHEMBL4064309 | 0.82 | NOTUM (0.41) | ALDH1A1RXRAKDM4EHPGDMAPK1 | |
| SCHEMBL13848115 | 0.79 | MAPT (0.38) | ALDH1A1RXRATP53KDM4ESMN1; SMN2 | |
| SCHEMBL10246545 | 0.76 | THRA (0.42) | ALDH1A1RXRAL3MBTL1MEN1KMT2A | |
| SCHEMBL13848300 | 0.76 | HDAC1 (0.36) | — | |
| SCHEMBL17948586 | 0.75 | RXRA (0.39) | ALDH1A1RXRATP53TSHRHPGD | |
| SCHEMBL13848091 | 0.75 | IDO1 (0.39) | L3MBTL1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL17948694 | 0.75 | TP53 (0.36) | RXRATP53TSHRNPSR1CNR2 | |
| SCHEMBL17948588 | 0.75 | CNR2 (0.38) | ALDH1A1RXRATP53TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |