SCHEMBL13848288

SCHEMBL13848288

CCCCOc1cc(OCCCC)c(C(C)C)cc1-c1ncoc1-c1ccccc1CC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.37
CYP19A1 P11511 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
CNR2 P34972 7/20 0.35
RXRA P19793 1/20 0.33
L3MBTL1 Q9Y468 4/20 0.33
MAPT P10636 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
FAAH O00519 2/20 0.32
HPGD P15428 1/20 0.32
ATM Q13315 1/20 0.32
P2RY1 P47900 1/20 0.32
PTGES O14684 1/20 0.32
ALOX5 P09917 1/20 0.32
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TSHR P16473 2/20 0.31
TRPV1 Q8NER1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4071442 0.87 BRD4 (0.38) RXRAMAPTHPGDPTGER1MAPK1
SCHEMBL13848452 0.86 MAPK14 (0.37) CYP1A2CYP19A1CYP2C9CYP2C19RXRA
SCHEMBL13848292 0.85 CYP1A2 (0.35) CYP1A2CYP19A1CYP2C9CYP2C19CNR2
SCHEMBL13848091 0.80 IDO1 (0.39) CYP1A2CYP19A1CYP2C9CYP2C19L3MBTL1
SCHEMBL13848290 0.78 HDAC1 (0.43) MAPTHPGDALDH1A1TRPV1MAPK1
SCHEMBL13848472 0.78 KCNH2 (0.36) MAPTTRPV1
SCHEMBL4071241 0.78 HSP90AA1 (0.43) CYP1A2CYP2C9CYP2C19MAPTNPSR1
SCHEMBL13848073 0.77 CYP19A1 (0.45) CYP1A2CYP19A1CYP2C9CYP2C19RXRA
SCHEMBL13848381 0.76 RXRA (0.41) CNR2RXRAL3MBTL1PTGESALOX5
SCHEMBL13848415 0.74 ALDH1A1 (0.36) CNR2RXRAL3MBTL1NPSR1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009066060-A2 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE TOPOTARGET A/S (DK) 2009-05-28 WO disclosed