Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848091 | 0.90 | IDO1 (0.39) | HDAC1HDAC6SMN1; SMN2HPGDMEN1 | |
| SCHEMBL13848452 | 0.85 | MAPK14 (0.37) | — | |
| SCHEMBL4063295 | 0.84 | MAPT (0.46) | SMN1; SMN2ALDH1A1HPGDNPC1LMNA | |
| SCHEMBL13848472 | 0.83 | KCNH2 (0.36) | TRPV1SMN1; SMN2MEN1NPC1KMT2A | |
| SCHEMBL13848073 | 0.80 | CYP19A1 (0.45) | SMN1; SMN2ALDH1A1HPGDNPC1HSD17B10 | |
| SCHEMBL13848385 | 0.79 | TSHR (0.44) | SMN1; SMN2HPGDMEN1NPC1KMT2A | |
| SCHEMBL4072459 | 0.78 | HSP90AA1 (0.46) | HDAC1HDAC6ALDH1A1HPGDTUBB4A | |
| SCHEMBL13848288 | 0.78 | CYP1A2 (0.37) | TRPV1ALDH1A1HPGDMAPK1MAPT | |
| SCHEMBL4070477 | 0.78 | TUBB4A (0.44) | HDAC1HDAC6TRPV1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13848378 | 0.78 | RAB9A (0.47) | SMN1; SMN2HPGDMEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |