Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848365 | 0.88 | ALDH1A1 (0.61) | MEN1KMT2AMAPTHTTPGAM1 | |
| SCHEMBL13848441 | 0.87 | STAT3 (0.57) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL13848266 | 0.82 | L3MBTL1 (0.54) | MEN1KMT2ASMN1; SMN2PGAM1CYP17A1 | |
| SCHEMBL13848258 | 0.81 | PGAM1 (0.56) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL1035847 | 0.79 | MEN1 (1.00) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL13848445 | 0.77 | MRGPRX1 (0.43) | PGAM1HTR6CYP17A1 | |
| SCHEMBL13848277 | 0.77 | PARP14 (0.46) | MAPTPGAM1CYP17A1LMNAHSD17B10 | |
| SCHEMBL13848473 | 0.76 | ALDH1A1 (0.54) | MEN1KMT2AMAPTHTTCYP17A1 | |
| SCHEMBL12878224 | 0.74 | MEN1 (0.74) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL13848448 | 0.74 | ALDH1A1 (0.48) | MEN1KMT2AMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |