Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848365 | 0.90 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL13848367 | 0.87 | MEN1 (0.65) | KMT2AMEN1LMNAMAPTPOLB | |
| SCHEMBL13848448 | 0.85 | ALDH1A1 (0.48) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL13848266 | 0.82 | L3MBTL1 (0.54) | ALDH1A1KDM4EKMT2AMEN1L3MBTL1 | |
| SCHEMBL13848337 | 0.81 | ALDH1A1 (0.57) | STAT3ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL4544247 | 0.80 | HSD17B10 (0.47) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL7571620 | 0.78 | POLB (0.68) | STAT3ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL13848277 | 0.77 | PARP14 (0.46) | LMNAMAPTNOD2HPGD | |
| SCHEMBL13848445 | 0.77 | MRGPRX1 (0.43) | L3MBTL1 | |
| SCHEMBL13848473 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KDM4EKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |