Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310248 | 0.81 | BCHE (0.39) | PDK2OPRL1ALDH1A1ALOX15MEN1 | |
| SCHEMBL21880254 | 0.80 | BCHE (0.35) | PDK2ALOX15MEN1KMT2ATDP1 | |
| SCHEMBL7322303 | 0.80 | P2RX1 (0.44) | ALOX15MEN1KMT2ATDP1LMNA | |
| SCHEMBL13940072 | 0.74 | PDK2 (0.40) | PDK2OPRL1ALOX15MEN1KMT2A | |
| SCHEMBL14181845 | 0.74 | APP (0.34) | PDK2ALDH1A1HSD17B10TSHRALOX15 | |
| SCHEMBL22169961 | 0.72 | POLB (0.31) | — | |
| SCHEMBL888093 | 0.71 | NPC1 (0.40) | ALDH1A1HSD17B10RAB9ANPC1MAPK1 | |
| SCHEMBL7320476 | 0.70 | LMNA (0.42) | PDK2OPRL1ALDH1A1HPGDMEN1 | |
| SCHEMBL15619729 | 0.70 | POLB (0.57) | PDK2ALDH1A1TSHRHPGDMEN1 | |
| SCHEMBL11766016 | 0.68 | ALDH1A1 (0.45) | PDK2OPRL1ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305026-B1 | BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS | NOVUSPHARMA SPA (IT) | 2009-05-13 | — | — | EP | disclosed |