Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13484335 | 0.82 | SLC6A3 (0.34) | KDM4EALDH1A1GAAALOX15CYP2A6 | |
| SCHEMBL13484020 | 0.74 | ENPP3 (0.44) | KDM4EALDH1A1GAAALOX15CYP2A6 | |
| SCHEMBL13744630 | 0.73 | ENPP3 (0.42) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL13484326 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1GAAALOX15NPC1 | |
| SCHEMBL13484328 | 0.70 | TSHR (0.46) | KDM4EALDH1A1ALOX15NPC1HSD17B10 | |
| SCHEMBL13848516 | 0.69 | S1PR1 (0.39) | KDM4EALDH1A1NPC1HSD17B10LMNA | |
| SCHEMBL13744533 | 0.69 | HTR2C (0.33) | TSHR | |
| SCHEMBL13484397 | 0.68 | ADORA2A (0.38) | KDM4EALDH1A1ALOX15HSD17B10MAPT | |
| SCHEMBL13848635 | 0.68 | CYP2A6 (0.43) | KDM4EALDH1A1ALOX15CYP2A6NPC1 | |
| SCHEMBL13848589 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549624-B1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | SCRIPPS RESEARCH INST (US) | 2009-05-13 | — | — | EP | disclosed |