Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13852792 | 0.80 | BAZ2B (0.48) | KDM4EALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL13852796 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL8278070 | 0.69 | DRD2 (0.58) | KDM4EALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL14398035 | 0.68 | BAZ2B (0.60) | KDM4EALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL13852919 | 0.67 | CYP1A2 (0.67) | KDM4EALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL8794276 | 0.66 | KDM4E (0.68) | KDM4EALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL7850778 | 0.65 | CYP1A2 (0.53) | KDM4EALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL8036235 | 0.65 | BAZ2B (0.57) | KDM4EALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL12602172 | 0.65 | MDH2 (0.58) | KDM4EALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL6234998 | 0.64 | KDM4E (0.65) | KDM4EALDH1A1HPGDMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131407-A1 | TETRACYCLIC KINASE INHIBITORS | GENENTECH, INC. | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131407-A1 | TETRACYCLIC KINASE INHIBITORS | CNKSR1, MAP3K19, BRAF | KDM4E 1144/4885ALDH1A1 3634/4885HPGD 4252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.