Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14184556 | 0.92 | TSHR (0.38) | TSHRUSP2MEN1KMT2ACHRM2 | |
| SCHEMBL16342116 | 0.88 | TSHR (0.38) | TSHRUSP2MEN1KMT2ACHRM2 | |
| SCHEMBL16425265 | 0.88 | TSHR (0.38) | TSHRUSP2MEN1KMT2ACHRM2 | |
| SCHEMBL12659539 | 0.82 | TSHR (0.33) | TSHRMEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL12659581 | 0.82 | TSHR (0.33) | TSHRMEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL16920462 | 0.82 | TSHR (0.33) | TSHRMEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL16425266 | 0.82 | TSHR (0.33) | TSHRMEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL19774492 | 0.80 | SMN1; SMN2 (0.36) | TSHRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL13415809 | 0.76 | TSHR (0.48) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL4148562 | 0.74 | TSHR (0.46) | TSHRCHRM2CHRM4CHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090123391-A1 | Novel Formulations | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-05-14 | — | — | US | disclosed |
| US-20080112894-A1 | N,N'-ethylenebis(acetyloligolactyl)amide comprising ethylenediamine amidated on both ends with polylactic acid having esterified end groups; use with drugs in a metered dose inhaler; stability enhanced by keeping hydroxyl end group impurities low | 3M INNOVATIVE PROPERTIES COMPANY | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090123391-A1 | Novel Formulations | PFN1, CCL11, MFAP1 | TSHR 3030/4885USP2 1147/4885MEN1 1647/4885 |
| US-20080112894-A1 | N,N'-ethylenebis(acetyloligolactyl)amide comprising ethylenediamine amidated on both ends with polylactic acid having esterified end groups; use with drugs in a metered dose inhaler; stability enhanced by keeping hydroxyl end group impurities low | SIGMAR1, OXER1, OPRM1 | TSHR 289/4885USP2 2301/4885MEN1 2814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.