SCHEMBL13853202

SCHEMBL13853202

C=CC(=O)OC(COc1ccc(-c2ccccc2)cc1)COc1cccc(OCOc2ccc(-c3ccccc3)cc2)c1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
MAPT P10636 1/20 0.40
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
FFAR4 Q5NUL3 4/20 0.39
FFAR1 O14842 2/20 0.39
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HTR1D P28221 1/20 0.37
HTR1B P28222 1/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4194694 0.96 THRB (0.46) THRBMAPTRXRARXRBFFAR4
SCHEMBL13853210 0.94 THRB (0.48) THRBMAPTLMNAPOLBGAA
SCHEMBL4192596 0.93 RXRA (0.47) THRBMAPTRXRARXRBFFAR4
SCHEMBL13853209 0.92 HTR1D (0.45) THRBFFAR4FFAR1LMNAMAPK1
SCHEMBL4202631 0.91 THRB (0.46) THRBMAPTRXRARXRBFFAR4
SCHEMBL4198439 0.90 RXRA (0.46) THRBRXRARXRBFFAR4FFAR1
SCHEMBL4186164 0.90 MAPT (0.48) THRBMAPTFFAR1LMNA
SCHEMBL4186231 0.90 MAPT (0.48) THRBMAPTFFAR1LMNA
SCHEMBL14546497 0.90 THRB (0.51) THRBMAPTLMNAGAA
SCHEMBL11957662 0.90 THRB (0.51) THRBLMNAMAPK1L3MBTL1HTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534909-B2 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2009-05-19 US disclosed
US-20070078198-A1 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2007-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078198-A1 (Meth) acrylic ester compound and use thereof METTL14, PAM, TAS2R41 THRB 1009/4885MAPT 2073/4885RXRA 360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.