Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.52 |
| ▸ | HTR3B | O95264 | 3/20 | 0.52 |
| ▸ | HTR3A | P46098 | 3/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.52 |
| ▸ | PNMT | P11086 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13887515 | 0.87 | GRIN2D (0.43) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL21594393 | 0.82 | HTR3E (0.56) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL13855830 | 0.79 | TSHR (0.38) | GRIN2BCYP3A4IDO1 | |
| SCHEMBL13615362 | 0.79 | IDO1 (0.33) | IDO1 | |
| SCHEMBL13855839 | 0.78 | MIF (0.53) | TAAR1GRIN2BIDO1AGXT | |
| SCHEMBL13921682 | 0.78 | MAOB (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL16097145 | 0.78 | TAAR1 (0.46) | TAAR1IDO1AGXT | |
| SCHEMBL14872978 | 0.78 | PDE2A (0.39) | GRIN2BSIGMAR1CYP3A4IDO1 | |
| SCHEMBL14648573 | 0.78 | TAAR1 (0.46) | TAAR1IDO1 | |
| SCHEMBL18795026 | 0.78 | CYP1A2 (0.53) | GRIN2BSIGMAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409293-B | Benzothiazinone compound, preparation method thereof and application of compound as antituberculosis drug | 苏州大学 | 2023-04-07 | — | — | CN | disclosed |
| WO-2021137665-A1 | 1, 2, 3-TRIAZOLE DERIVATIVE COMPOUND AS HSP90 INHIBITOR, AND USE THEREOF | 이화여자대학교 산학협력단 | 2021-07-08 | — | — | WO | disclosed |
| WO-2021137665-A1 | 1, 2, 3-TRIAZOLE DERIVATIVE COMPOUND AS HSP90 INHIBITOR, AND USE THEREOF | 이화여자대학교 산학협력단 | 2021-07-08 | — | — | WO | disclosed |
| CN-112409293-A | Benzothiazinone compound, preparation method thereof and application of compound as antituberculosis drug | 苏州大学 | 2021-02-26 | — | — | CN | disclosed |
| WO-2020232807-A1 | NAPHTHOQUINONE FUSED TRIAZOLE DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | 广州中医药大学(广州中医药研究院) (CN) | 2020-11-26 | — | — | WO | disclosed |
| CN-111269197-A | Benzothiazinone compound, preparation method thereof and application of compound as antituberculosis drug | 苏州大学 | 2020-06-12 | — | — | CN | disclosed |
| CN-104497008-B | Substituted (oxazolidinon-5-yl-methyl)-2-thiophene-carboxamides compound and using method thereof and purposes | 广东东阳光药业有限公司 | 2016-11-16 | — | — | CN | disclosed |
| US-9051281-B2 | Compounds | GLAXOSMITHKLINE LLC (US) | 2015-06-09 | — | — | US | disclosed |
| US-9051281-B2 | Compounds | GLAXOSMITHKLINE LLC (US) | 2015-06-09 | — | — | US | disclosed |
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |
| EP-2368887-B1 | 1, 2, 3-TRIAZOLE DERIVATIVES FOR USE AS STEAROYL-COA DESATURASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2014-02-26 | — | — | EP | disclosed |
| US-20130281499-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2013-10-24 | — | — | US | disclosed |
| US-20130281499-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2013-10-24 | — | — | US | disclosed |
| US-8486977-B2 | 1,2,3-triazole derivatives for use as stearoyl-CoA desaturase inhibitors | GLAXOSMITHKLINE LLC (US) | 2013-07-16 | — | — | US | disclosed |
| US-8486977-B2 | 1,2,3-triazole derivatives for use as stearoyl-CoA desaturase inhibitors | GLAXOSMITHKLINE LLC (US) | 2013-07-16 | — | — | US | disclosed |
| CN-103059003-A | Benzimidazole-1,2,3-triazole compound having antifungal activity, and its preparation method | UNIV HENAN NORMAL | 2013-04-24 | — | — | CN | disclosed |
| EP-2368887-A1 | 1, 2, 3-triazole derivatives for use as stearoyl-COA desaturase inhibitors | Glaxosmithkline LLC (US) | 2011-09-28 | — | — | EP | disclosed |
| US-20100297054-A1 | 1,2,3-TRIAZOLE DERIVATIVES FOR USE AS STEAROYL-COA DESATURASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION | 2010-11-25 | — | — | US | disclosed |
| US-20100297054-A1 | 1,2,3-TRIAZOLE DERIVATIVES FOR USE AS STEAROYL-COA DESATURASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION | 2010-11-25 | — | — | US | disclosed |
| WO-2009060053-A1 | 1, 2, 3-TRIAZOLE DERIVATIVES FOR USE AS STEAROYL-COA DESATURASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297054-A1 | 1,2,3-TRIAZOLE DERIVATIVES FOR USE AS STEAROYL-COA DESATURASE INHIBITORS | SCD, SCD5, FASN | HTR3E 1690/4885HTR3B 1738/4885HTR3A 1357/4885 |
| US-20130281499-A1 | COMPOUNDS | CYP11B2, SCD, CYP11B1 | HTR3E 1167/4885HTR3B 755/4885HTR3A 1432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.