Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 7/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 10/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385847 | 0.89 | CASR (0.55) | CASRRIPK1TMEM97SIGMAR1 | |
| SCHEMBL1385867 | 0.83 | CASR (0.59) | CASRRIPK1MAPT | |
| SCHEMBL1385738 | 0.83 | CASR (0.46) | CASRTMEM97SIGMAR1 | |
| SCHEMBL1386100 | 0.81 | CASR (0.56) | CASRRIPK1 | |
| SCHEMBL1386946 | 0.81 | CASR (0.46) | CASRTMEM97SIGMAR1 | |
| SCHEMBL3951753 | 0.80 | CASR (0.37) | CASRTP53MAPT | |
| SCHEMBL1383382 | 0.79 | CASR (0.46) | CASRTMEM97SIGMAR1TP53MAPT | |
| SCHEMBL1386625 | 0.79 | CASR (0.59) | CASRRIPK1SIGMAR1TP53MAPT | |
| SCHEMBL1383373 | 0.79 | CASR (0.55) | CASRTMEM97SIGMAR1 | |
| SCHEMBL1383579 | 0.79 | CASR (0.55) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |