Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13858488 | 0.89 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CYP1A2CYP2C19GAA | |
| SCHEMBL5337127 | 0.86 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1CYP1A2CYP2C19GAA | |
| SCHEMBL13996135 | 0.85 | GAA (0.49) | ALDH1A1L3MBTL1CYP1A2CYP2C19GAA | |
| SCHEMBL13858739 | 0.84 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1CYP1A2CYP2C19GAA | |
| SCHEMBL11781754 | 0.84 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1CYP1A2CYP2C19GAA | |
| SCHEMBL4005253 | 0.83 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1CYP1A2CYP2C19GAA | |
| SCHEMBL6814154 | 0.83 | L3MBTL1 (0.48) | ALDH1A1L3MBTL1CYP1A2CYP2C19GAA | |
| SCHEMBL5535275 | 0.83 | GAA (0.47) | ALDH1A1L3MBTL1CYP1A2CYP2C19GAA | |
| SCHEMBL30902486 | 0.81 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1CYP1A2CYP2C19GAA | |
| SCHEMBL13858741 | 0.81 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1CYP1A2CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212196-B2 | Hypophosphorous acid derivatives having antihyperalgic activity and biological applications thereof | UNIVERSITE PARIS DESCARTES (FR) | 2015-12-15 | — | — | US | disclosed |
| US-20140107078-A1 | HYPOPHOSPHOROUS ACID DERIVATIVES HAVING ANTIHYPERALGIC ACTIVITY AND BIOLOGICAL APPLICATIONS THEREOF | UNIVWESITE D"AUVERGNE (FR) | 2014-04-17 | — | — | US | disclosed |
| WO-2012156931-A1 | HYPOPHOSPHOROUS ACID DERIVATIVES HAVING ANTIHYPERALGIC ACTIVITY AND BIOLOGICAL APPLICATIONS THEREOF | UNIVERSITE PARIS DESCARTES (FR) | 2012-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107078-A1 | HYPOPHOSPHOROUS ACID DERIVATIVES HAVING ANTIHYPERALGIC ACTIVITY AND BIOLOGICAL APPLICATIONS THEREOF | HCAR3, HRH3, SSTR3 | ALDH1A1 1395/4885L3MBTL1 4087/4885CYP1A2 1041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.