Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712322 | 0.98 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL5712324 | 0.88 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL13858488 | 0.84 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL13858951 | 0.83 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL4003957 | 0.81 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL4007449 | 0.80 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL4005149 | 0.76 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1KMT2AMEN1HPGD | |
| SCHEMBL14195847 | 0.76 | S1PR2 (0.53) | ALDH1A1L3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL29954609 | 0.76 | ALDH1A1 (0.78) | ALDH1A1L3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL10497234 | 0.75 | FDPS (0.46) | ALDH1A1L3MBTL1TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383736-B1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| US-6967220-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2005-11-22 | — | — | US | disclosed |
| US-20040106795-A1 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106795-A1 | Peptide deformylase inhibitors | PDF, PEPD, DPEP1 | ALDH1A1 4367/4885L3MBTL1 1436/4885TDP1 473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.