Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947763 | 0.91 | ALOX5 (0.43) | ALOX5KMT2ASMN1; SMN2LTB4RLTB4R2 | |
| SCHEMBL3941835 | 0.90 | ALOX5 (0.46) | ALOX5KMT2ASMN1; SMN2CYP2C9LTB4R | |
| SCHEMBL3942439 | 0.88 | ALOX5 (0.38) | ALOX5KMT2ACYP2C9ADRB2ADRB3 | |
| SCHEMBL3951648 | 0.84 | TSPO (0.37) | ALOX5PPARGNR1H4TSPO | |
| SCHEMBL3942434 | 0.81 | ALOX5 (0.41) | ALOX5KMT2ASMN1; SMN2CYP2C9LTB4R | |
| SCHEMBL1386007 | 0.81 | MEN1 (0.42) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3951984 | 0.80 | SMN1; SMN2 (0.38) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3945147 | 0.79 | TSPO (0.37) | KMT2ACYP2C9ADRB2MEN1TSPO | |
| SCHEMBL3946482 | 0.79 | ALOX5 (0.39) | ALOX5KMT2ACYP2C9ADRB2ADRB3 | |
| SCHEMBL1383618 | 0.78 | ALOX5 (0.47) | ALOX5KMT2ASMN1; SMN2CYP2C9LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718632-B1 | PYRIMIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SANOFI AVENTIS (FR) | 2009-04-22 | — | — | EP | claimed |