SCHEMBL13864971

SCHEMBL13864971

COC(=O)c1cccc(C(=O)Oc2c(C)cc(Cc3cc(C)c(C)c(C)c3)cc2C)c1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LOXL2 Q9Y4K0 2/20 0.49
▸ CYP4F2 P78329 2/20 0.48
▸ CYP4A11 Q02928 2/20 0.48
▸ SLC7A5 Q01650 1/20 0.43
▸ RAB9A P51151 4/20 0.42
▸ MAPT P10636 2/20 0.42
▸ LMNA P02545 2/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ NPC1 O15118 2/20 0.42
▸ TSHR P16473 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.40
▸ MRGPRX4 Q96LA9 2/20 0.40
▸ POLB P06746 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13018407 0.91 LOXL2 (0.46) LOXL2CYP4F2CYP4A11SLC7A5RAB9A
SCHEMBL13864915 0.90 TDP1 (0.47) LOXL2CYP4F2CYP4A11RAB9AMAPT
SCHEMBL17756688 0.87 LOXL2 (0.45) LOXL2CYP4F2CYP4A11RAB9AMAPT
SCHEMBL13865029 0.86 CA12 (0.49) LOXL2CYP4A11RAB9AMAPTLMNA
SCHEMBL13030401 0.84 MAPT (0.44) LOXL2RAB9AMAPTLMNAL3MBTL1
SCHEMBL12762425 0.84 ALDH1A1 (0.40) LOXL2CYP4F2CYP4A11RAB9AMAPT
SCHEMBL13864962 0.83 LOXL2 (0.42) LOXL2CYP4F2CYP4A11RAB9AMAPT
SCHEMBL16573859 0.83 MAPT (0.46) LOXL2CYP4F2CYP4A11RAB9AMAPT
SCHEMBL13864990 0.82 PPARA (0.44) LOXL2CYP4F2CYP4A11SLC7A5RAB9A
SCHEMBL13865014 0.82 KDM4E (0.44) MAPTLMNATSHRALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090123854-A1 IMAGE FORMING METHOD KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-05-14 — — US disclosed
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