Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31464207 | 0.67 | — | — | |
| SCHEMBL7212975 | 0.67 | — | — | |
| SCHEMBL1426918 | 0.63 | ADRA2C (0.36) | ADRA2CKMT2AMEN1PABPC1 | |
| SCHEMBL12308687 | 0.62 | NFKB1 (0.32) | ADRA2C | |
| Hydrochloric Acid SCHEMBL3119370 | 0.62 | ADRA2C (0.35) | ADRA2CKMT2AMEN1PABPC1 | |
| SCHEMBL13391600 | 0.60 | ADRA2C (0.42) | ADRA2CKMT2AMEN1PABPC1MAPK1 | |
| SCHEMBL8826943 | 0.60 | ADRA2C (0.42) | ADRA2CKMT2AMEN1PABPC1MAPK1 | |
| SCHEMBL155376 | 0.58 | — | — | |
| SCHEMBL24385155 | 0.57 | ALDH1A1 (0.41) | — | |
| SCHEMBL10035468 | 0.56 | GSK3A (0.33) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131444-A1 | Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity | ASTRAZENECA AB (SE) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131444-A1 | Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity | AAAS, AMPD2, AMPD3 | ADRA2C 617/4885KMT2A 889/4885MEN1 1987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.