SCHEMBL13867939

SCHEMBL13867939

Cc1ccc(N(c2ccc(C)c(C)c2)c2cc3c4cc(C)c(C)cc4c(N(c4ccc(C)c(C)c4)c4ccc(C)c(C)c4)cc3c3cc(C)c(C)cc23)cc1C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
S1PR1 P21453 1/20 0.32
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13775210 0.93
SCHEMBL13775183 0.87 ALDH1A1 (0.33) ALDH1A1NPC1LMNARAB9ASMN1; SMN2
SCHEMBL1376567 0.86 CYP1A2 (0.38) ALDH1A1S1PR1
SCHEMBL20115617 0.86 CYP1A2 (0.39) S1PR1
SCHEMBL13775209 0.85 KDM1A (0.32) S1PR1
SCHEMBL13775212 0.85 KDM1A (0.32) S1PR1
SCHEMBL13775270 0.85 ALDH1A1 (0.34) ALDH1A1S1PR1NPC1LMNARAB9A
SCHEMBL13775196 0.83 ALDH1A1 (0.39) ALDH1A1
SCHEMBL18978244 0.82 S1PR1 (0.36) ALDH1A1S1PR1
SCHEMBL13775187 0.82 LMNA (0.40) S1PR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524568-B2 Aromatic amine derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2009-04-28 US disclosed
US-7524568-B2 Aromatic amine derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2009-04-28 US disclosed
US-20080268283-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-10-30 US disclosed
US-20080268283-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-10-30 US disclosed
US-7425653-B2 Aromatic amine derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2008-09-16 US disclosed
US-7425653-B2 Aromatic amine derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2008-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080268283-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME TYR, MAOA, AOC2 ALDH1A1 460/4885S1PR1 4540/4885NPC1 4520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.