Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17775103 | 0.84 | GRM5 (0.34) | — | |
| SCHEMBL30198023 | 0.84 | GRM5 (0.34) | — | |
| SCHEMBL31058250 | 0.81 | AR (0.37) | VCAM1ESR2 | |
| SCHEMBL10041745 | 0.81 | AR (0.37) | VCAM1ESR2 | |
| SCHEMBL13868346 | 0.80 | ESR2 (0.33) | ESR2 | |
| SCHEMBL13878853 | 0.78 | LPL (0.36) | ESR2 | |
| SCHEMBL16826644 | 0.78 | LPL (0.40) | — | |
| SCHEMBL15414938 | 0.77 | GPR35 (0.48) | — | |
| SCHEMBL13868338 | 0.73 | MAPK1 (0.32) | VCAM1ESR2 | |
| SCHEMBL22366912 | 0.72 | TRPV4 (0.33) | VCAM1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514563-B2 | Producing cyano-substituted pyridine, pyrrole, furan, thiophene or benzene boranes by reacting a cyanoarene with a BH or a HBBH compound, especially 4,4,5,5-tetramethyl-1,3,2-dioxborolane or its dimer, in the presence of an organo-phosphorus or -nitrogen iridium complex; drug intermediates | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2009-04-07 | — | — | US | disclosed |
| US-7514563-B2 | Producing cyano-substituted pyridine, pyrrole, furan, thiophene or benzene boranes by reacting a cyanoarene with a BH or a HBBH compound, especially 4,4,5,5-tetramethyl-1,3,2-dioxborolane or its dimer, in the presence of an organo-phosphorus or -nitrogen iridium complex; drug intermediates | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2009-04-07 | — | — | US | disclosed |