Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31058250 | 1.00 | AR (0.37) | ARVCAM1PDK1PDK2PDK3 | |
| SCHEMBL931715 | 0.82 | CYP2A6 (0.35) | ARESR2PDE4BCYP11B2CHRM1 | |
| SCHEMBL30101113 | 0.82 | CYP2A6 (0.35) | ARESR2PDE4BCYP11B2CHRM1 | |
| SCHEMBL12069815 | 0.81 | AR (0.33) | ARVCAM1PDK1PDK2PDK3 | |
| SCHEMBL30372881 | 0.81 | ALDH1A1 (0.36) | ESR2PDE4BCHRM1PDE4AADRA1A | |
| SCHEMBL15549421 | 0.81 | LPL (0.37) | ESR2JAK2BTKCYP11B2LPL | |
| SCHEMBL22637023 | 0.81 | ALDH1A1 (0.36) | ESR2PDE4BCHRM1PDE4AADRA1A | |
| SCHEMBL29358185 | 0.81 | CYP11B2 (0.38) | ESR2PDE4BJAK2BTKCYP11B2 | |
| SCHEMBL156525 | 0.81 | CYP11B2 (0.38) | ESR2PDE4BJAK2BTKCYP11B2 | |
| SCHEMBL13868337 | 0.81 | VCAM1 (0.31) | VCAM1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078119-A1 | DEGRADER COMPOUNDS AND USES THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2026-03-19 | — | — | US | disclosed |
| EP-4688771-A1 | NOVEL FAK DEGRADER COMPOUNDS AND USES THEREOF | Bristol-Myers Squibb Company (US) | 2026-02-11 | — | — | EP | disclosed |
| US-20250368667-A1 | USP1 INHIBITOR | SHANGHAI QILU PHARMACEUTICAL RES AND DEVELOPMENT CENTRE LTD (CN) | 2025-12-04 | — | — | US | disclosed |
| EP-4582427-A1 | USP1 INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2025-07-09 | — | — | EP | disclosed |
| US-20240109900-A1 | AZABICYCLIC SHP2 INHIBITORS | PROMIDIS S.R.L. (IT) | 2024-04-04 | — | — | US | disclosed |
| EP-4288431-A1 | AZABICYCLIC SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167682-A1 | AZABICYCLIC SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2022-08-11 | — | — | WO | disclosed |
| US-11021484-B2 | Compound including nitrogen and organic electroluminescence device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-06-01 | — | — | US | disclosed |
| EP-3460863-A1 | COMPOUND INCLUDING NITROGEN AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | Samsung Display Co., Ltd. (KR) | 2019-03-27 | — | — | EP | disclosed |
| US-20190084992-A1 | COMPOUND INCLUDING NITROGEN AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-03-21 | — | — | US | disclosed |
| US-20130274243-A1 | Chemical Compounds | PFIZER LTD (GB) | 2013-10-17 | — | — | US | disclosed |
| WO-2013114250-A1 | BENZIIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AS SODIUM CHANNEL MODULATORS | PFIZER INC. (US) | 2013-08-08 | — | — | WO | disclosed |
| US-20130096141-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME CORP. | 2013-04-18 | — | — | US | disclosed |
| US-8368062-B2 | Nitrogen-containing heterocyclic compound and organic electronic device using the same | LG CHEM, LTD. (KR) | 2013-02-05 | — | — | US | disclosed |
| US-8368062-B2 | Nitrogen-containing heterocyclic compound and organic electronic device using the same | LG CHEM, LTD. (KR) | 2013-02-05 | — | — | US | disclosed |
| US-20120007069-A1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2012-01-12 | — | — | US | disclosed |
| US-20120007069-A1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2012-01-12 | — | — | US | disclosed |
| WO-2011159657-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME CORP. (US) | 2011-12-22 | — | — | WO | disclosed |
| US-20110127513-A1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2011-06-02 | — | — | US | disclosed |
| US-20110127513-A1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096141-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND METHODS OF USE THEREOF | GPR119, GCGR, GPR139 | AR 949/4885VCAM1 2175/4885PDK1 896/4885 |
| US-20240109900-A1 | AZABICYCLIC SHP2 INHIBITORS | PTPN22, PTPN2, PTPN5 | AR 3737/4885VCAM1 2610/4885PDK1 1286/4885 |
| US-20190084992-A1 | COMPOUND INCLUDING NITROGEN AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | OR10J3, L1CAM, NOS1 | AR 3042/4885VCAM1 1842/4885PDK1 3895/4885 |
| US-20130274243-A1 | Chemical Compounds | SCN8A, SCN5A, KCNJ8 | AR 3211/4885VCAM1 2812/4885PDK1 1763/4885 |
| US-20120007069-A1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | VDAC2, VDAC1, VDAC3 | AR 3579/4885VCAM1 4048/4885PDK1 3468/4885 |
| US-20260078119-A1 | DEGRADER COMPOUNDS AND USES THEREOF | CTTN, SRC, PTK2 | AR 121/4885VCAM1 1671/4885PDK1 1924/4885 |
| US-20250368667-A1 | USP1 INHIBITOR | USP1, USP2, USP28 | AR 4019/4885VCAM1 3809/4885PDK1 1242/4885 |
| US-20110127513-A1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | VDAC2, VDAC1, VDAC3 | AR 3579/4885VCAM1 4048/4885PDK1 3468/4885 |
| US-11021484-B2 | Compound including nitrogen and organic electroluminescence device including the same | OR10J3, L1CAM, NOS1 | AR 3042/4885VCAM1 1842/4885PDK1 3895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.