Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.36 |
| ▸ | TUBB | P07437 | 3/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 4/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10292844 | 0.91 | AVPR1A (0.34) | FYNPARP1PDK2 | |
| SCHEMBL13868664 | 0.91 | AVPR1A (0.34) | FYNPARP1PDK2 | |
| SCHEMBL10292658 | 0.89 | MGAM (0.38) | PARP1 | |
| SCHEMBL10293035 | 0.89 | PARP1 (0.35) | FYNPARP1PDK2 | |
| SCHEMBL24404156 | 0.88 | PDK2 (0.35) | PARP1PDK2 | |
| SCHEMBL10292865 | 0.88 | RAB9A (0.37) | FYNPARP1PDK2LMNA | |
| SCHEMBL10293037 | 0.88 | AVPR2 (0.34) | FYNPARP1PDK2LMNA | |
| SCHEMBL13868643 | 0.88 | AVPR2 (0.34) | FYNPARP1PDK2LMNA | |
| SCHEMBL13868637 | 0.88 | RAB9A (0.37) | FYNPARP1PDK2LMNA | |
| SCHEMBL10292866 | 0.87 | TUBB4A (0.37) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521004-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2009-04-21 | — | — | US | disclosed |
| US-7521004-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2009-04-21 | — | — | US | disclosed |
| EP-1674460-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2009-01-21 | — | — | EP | disclosed |
| US-20070215844-A1 | Chromene Compound | TOKUYAMA CORPORATION (JP) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070215844-A1 | Chromene Compound | CRY2, TYR, CRY1 | TUBB4A 2918/4885TUBB 1998/4885TUBA3C 2620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.