Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158281 | 0.85 | MAPT (0.50) | MAPTL3MBTL1NPSR1ALDH1A1HTT | |
| SCHEMBL22787328 | 0.84 | MAPT (0.44) | MAPTL3MBTL1NPSR1ALDH1A1HTT | |
| SCHEMBL12551855 | 0.82 | ALDH1A1 (0.41) | MAPTL3MBTL1NPSR1ALDH1A1HTT | |
| SCHEMBL13862935 | 0.81 | ALDH1A1 (0.42) | MAPTL3MBTL1NPSR1ALDH1A1HTT | |
| SCHEMBL9712162 | 0.80 | MAPT (0.40) | MAPTL3MBTL1NPSR1ALDH1A1HTT | |
| SCHEMBL13888142 | 0.78 | ALDH1A1 (0.46) | MAPTL3MBTL1NPSR1ALDH1A1HTT | |
| SCHEMBL13895401 | 0.77 | GABRA1 (0.43) | MAPTL3MBTL1NPSR1ALDH1A1HTT | |
| SCHEMBL15134175 | 0.76 | MAPT (0.37) | MAPTL3MBTL1NPSR1ALDH1A1HTT | |
| SCHEMBL13029008 | 0.76 | ALDH1A1 (0.41) | MAPTL3MBTL1NPSR1ALDH1A1HTT | |
| SCHEMBL23061057 | 0.75 | CYP3A4 (0.50) | MAPTL3MBTL1LMNAKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009062289-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-22 | — | — | WO | disclosed |