SCHEMBL13029008

SCHEMBL13029008

CCOc1ccc(-c2ccc(-c3ccc(CC)c(C)c3C)c(C)c2C)c(C)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.41
HTT P42858 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
KDM4E B2RXH2 7/20 0.41
MAPT P10636 4/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
HPGD P15428 3/20 0.37
HSD17B10 Q99714 3/20 0.37
FFAR4 Q5NUL3 2/20 0.36
LMNA P02545 1/20 0.36
NPC1 O15118 1/20 0.34
USP2 O75604 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPK1 P28482 1/20 0.34
PTPRC P08575 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13888142 0.81 ALDH1A1 (0.46) ALDH1A1HTTMEN1KMT2AMCOLN3
SCHEMBL13868786 0.76 MAPT (0.42) ALDH1A1HTTMEN1KMT2AMCOLN3
SCHEMBL13895401 0.76 GABRA1 (0.43) ALDH1A1HTTMEN1KMT2AMCOLN3
SCHEMBL15119641 0.75 FFAR4 (0.43) ALDH1A1HTTMEN1KMT2AMCOLN3
SCHEMBL19365948 0.75 L3MBTL1 (0.58) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL15119636 0.74 ADORA3 (0.43) ALDH1A1HTTMEN1KMT2AMCOLN3
SCHEMBL5290521 0.74 MEN1 (0.53) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL17637326 0.74 KDM4E (0.51) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL15119718 0.74 FFAR4 (0.44) ALDH1A1HTTMEN1KMT2AMCOLN3
SCHEMBL17192242 0.73 KDM4E (0.41) ALDH1A1HTTMEN1KMT2AMCOLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8821992-B2 Oligosiloxane modified liquid crystal formulations and devices using same DOW CORNING CORPORATION (US) 2014-09-02 US disclosed
US-8368831-B2 Oligosiloxane modified liquid crystal formulations and devices using same DOW CORNING CORPORATION (US) 2013-02-05 US disclosed
US-20100283927-A1 OLIGOSILOXANE MODIFIED LIQUID CRYSTAL FORMULATIONS AND DEVICES USING SAME DOW CORNING CORPORATION (US) 2010-11-11 US disclosed
US-20100283925-A1 OLIGOSILOXANE MODIFIED LIQUID CRYSTAL FORMULATIONS AND DEVICES USING SAME DOW CORNING CORPORATION (US) 2010-11-11 US disclosed