Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13868786 | 0.85 | MAPT (0.42) | MAPTKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10158064 | 0.81 | CSNK2A1 (0.45) | MAPTKDM4EALDH1A1HPGDCSNK2A1 | |
| SCHEMBL12551855 | 0.79 | ALDH1A1 (0.41) | MAPTKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL17637321 | 0.73 | KDM4E (0.68) | MAPTKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL17192245 | 0.72 | ALDH1A1 (0.51) | MAPTKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10158646 | 0.72 | CTRC (0.40) | MAPTALDH1A1POLBL3MBTL1HTT | |
| SCHEMBL13862857 | 0.71 | ALDH1A1 (0.45) | MAPTKDM4EALDH1A1HPGDCSNK2A1 | |
| SCHEMBL27426795 | 0.70 | MAPT (0.45) | MAPTKDM4EALDH1A1HPGDCSNK2A1 | |
| SCHEMBL8083661 | 0.70 | RAB9A (0.49) | MAPTALDH1A1HPGDCSNK2A1L3MBTL1 | |
| SCHEMBL15801288 | 0.70 | MAPT (0.62) | MAPTKDM4EALDH1A1HPGDCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220076-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INT (DE) | 2012-01-18 | — | — | EP | disclosed |
| WO-2009062288-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-22 | — | — | WO | disclosed |