Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | LTB4R | Q15722 | 8/20 | 0.57 |
| ▸ | LTB4R2 | Q9NPC1 | 8/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ESRRG | P62508 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219225 | 0.92 | KMT2A (0.74) | KMT2ALTB4RLTB4R2RAB9ANPC1 | |
| SCHEMBL13869716 | 0.88 | KMT2A (0.84) | KMT2ARAB9ANPC1L3MBTL1MEN1 | |
| SCHEMBL8506886 | 0.82 | KMT2A (0.57) | KMT2ALTB4RLTB4R2RAB9ANPC1 | |
| SCHEMBL12017300 | 0.82 | KMT2A (0.60) | KMT2ALTB4RLTB4R2RAB9ANPC1 | |
| SCHEMBL8188967 | 0.82 | KMT2A (0.70) | KMT2ALTB4RLTB4R2RAB9ANPC1 | |
| SCHEMBL24095946 | 0.81 | ESRRG (0.49) | KMT2ALTB4RLTB4R2OPRM1OPRD1 | |
| SCHEMBL17117230 | 0.81 | ALOX5 (0.71) | KMT2ALTB4RLTB4R2RAB9ANPC1 | |
| SCHEMBL3959606 | 0.80 | KMT2A (0.55) | KMT2ALTB4RLTB4R2OPRM1OPRD1 | |
| SCHEMBL12133485 | 0.80 | LTB4R (0.58) | KMT2ALTB4RLTB4R2RAB9ANPC1 | |
| SCHEMBL4324200 | 0.80 | KMT2A (0.46) | KMT2AOPRM1OPRD1OPRK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | claimed |
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |